Substance / Medication

Retapamulin

Overview

Active Ingredient
retapamulin
RxNorm CUI
642274

Indications

2 Staphylococcus aureus Streptococcus pyogenes [see Clinical Studies (14)] ALTABAX is indicated for use in adults and pediatric patients aged 9 months and older for the topical treatment of impetigo (up to 100 cmin total area in adults or 2% total body surface area in pediatric patients aged 9 months or older) due to(methicillin-susceptible isolates only) or. To reduce the development of drug-resistant bacteria and maintain the effectiveness of ALTABAX and other antibacterial drugs, ALTABAX shou

Labeler: Rebel Distributors Corp.Updated: 2010-09-02T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

None.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

4 trials linked to this intervention

4
Total Trials
0
Recruiting
3
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Natural history of non-bullous impetigo: a systematic review of time to resolution or improvement without antibiotic treatment.
Hoffmann Tammy C, Peiris Ruwani, Glasziou Paul et al. · Br J Gen Pract · 2021
PMID: 33558328Meta-AnalysisFull text (PMC)
Emerging Treatment Strategies for Impetigo in Endemic and Nonendemic Settings: A Systematic Review.
Gahlawat Garima, Tesfaye Wubshet, Bushell Mary et al. · Clin Ther · 2021
PMID: 34053699Meta-Analysis
Prevalence of scabies and impetigo worldwide: a systematic review.
Romani Lucia, Steer Andrew C, Whitfeld Margot J et al. · Lancet Infect Dis · 2015
PMID: 26088526Meta-Analysis
The Global Epidemiology of Impetigo: A Systematic Review of the Population Prevalence of Impetigo and Pyoderma.
Bowen Asha C, Mahé Antoine, Hay Roderick J et al. · PLoS One · 2015
PMID: 26317533Meta-AnalysisFull text (PMC)
Interventions for impetigo.
Koning Sander, van der Sande Renske, Verhagen Arianne P et al. · Cochrane Database Syst Rev · 2012
PMID: 22258953Meta-AnalysisFull text (PMC)
Interventions for impetigo.
Koning S, Verhagen A P, van Suijlekom-Smit L W A et al. · Cochrane Database Syst Rev · 2004
PMID: 15106198Meta-Analysis
Topical retapamulin ointment, 1%, versus sodium fusidate ointment, 2%, for impetigo: a randomized, observer-blinded, noninferiority study.
Oranje Arnold P, Chosidow Olivier, Sacchidanand Sarvajnamurthy et al. · Dermatology · 2007
PMID: 17911992Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Retapamulin (substance)
SNOMED CT
427137002
UMLS CUI
C1703334
RxNorm CUI
642274
Labeler
Rebel Distributors Corp.

Clinical Data

This intervention maps to 2 entities in the Ltrl knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
4
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.