Substance / Medication

Sodium nitroprusside

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

3 trials linked to this intervention

3
Total Trials
0
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Sodium nitroprusside for advanced heart failure. A metanalysis of literature data.
Ghio S, Mandurino-Mirizzi A, La Rovere M T et al. · Vascul Pharmacol · 2023
PMID: 36563732Meta-Analysis
Comparison of sodium nitroprusside and adenosine for fractional flow reserve assessment: a systematic review and meta-analysis.
Solernó Raúl, Pedroni Pablo, Mariani Javier et al. · Expert Rev Cardiovasc Ther · 2018
PMID: 30122073Meta-Analysis
Does sodium nitroprusside kill babies? A systematic review.
Sass Nelson, Itamoto Caroline Harumi, Silva Marina Pereira et al. · Sao Paulo Med J · 2007
PMID: 17625709Meta-AnalysisFull text (PMC)
Sodium nitroprusside as an adjunctive treatment for schizophrenia reduces Ndel1 oligopeptidase activity.
Nani João Victor, Ushirohira Juliana Mayumi, Bradshaw Nicholas J et al. · Braz J Psychiatry · 2024
PMID: 37994832RCTFull text (PMC)
Treatment-resistant schizophrenia - A RCT on the effectiveness of repeated-dose sodium nitroprusside.
Adelino Marcelo P M, Nunes Marcel V, Nunes Marielle F Q et al. · Schizophr Res · 2021
PMID: 33773362RCT
The effects of sodium nitroprusside treatment on cognitive deficits in schizophrenia: a pilot study.
Maia-de-Oliveira Joao Paulo, Abrao Joao, Evora Paulo R et al. · J Clin Psychopharmacol · 2015
PMID: 25502490RCT
Rapid improvement of acute schizophrenia symptoms after intravenous sodium nitroprusside: a randomized, double-blind, placebo-controlled trial.
Hallak Jaime E C, Maia-de-Oliveira Joao Paulo, Abrao Joao et al. · JAMA Psychiatry · 2013
PMID: 23699763RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Sodium nitroprusside (substance)
SNOMED CT
387139005
UMLS CUI
C0037533

Clinical Data

This intervention maps to 10 entities in the Healos knowledge graph.

3
Conditions
4
Biomarkers
2
Specialists
0
Symptoms
3
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.