Substance / Medication

Tacrine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Multifunctional liposomes for nasal delivery of the anti-Alzheimer drug tacrine hydrochloride.
Corace Giuseppe, Angeloni Cristina, Malaguti Marco et al. · J Liposome Res · 2014
PMID: 24807822Observational
Response surface methodology to investigate the iontophoretic delivery of tacrine hydrochloride.
Upasani Rashmi S, Banga Ajay K · Pharm Res · 2004
PMID: 15648261Observational
The orthorhombic pseudopolymorph of tacrine hydrochloride.
Jacobs Jeroen, Moris Michele, De Samber Tim et al. · Acta Crystallogr B Struct Sci Cryst Eng Mater · 2016
PMID: 27698319Other
Application of design of experiments for formulation development and mechanistic evaluation of iontophoretic tacrine hydrochloride delivery.
Patel Niketkumar, Jain Shashank, Madan Parshotam et al. · Drug Dev Ind Pharm · 2016
PMID: 27100474Other
Microparticles based on chitosan/pectin polyelectrolyte complexes for nasal delivery of tacrine hydrochloride.
Saladini Bruno, Bigucci Federica, Cerchiara Teresa et al. · Drug Deliv Transl Res · 2013
PMID: 25787866Other
Solid-state characterization of tacrine hydrochloride.
Sorrenti Milena, Catenacci Laura, Bruni Giovanna et al. · J Pharm Biomed Anal · 2012
PMID: 22326286Other
Synthesis and in vitro evaluation of N-alkyl-7-methoxytacrine hydrochlorides as potential cholinesterase inhibitors in Alzheimer disease.
Korabecny Jan, Musilek Kamil, Holas Ondrej et al. · Bioorg Med Chem Lett · 2010
PMID: 20817518Other
Transdermal iontophoretic delivery of tacrine hydrochloride: Correlation between in vitro permeation and in vivo performance in rats.
Patel Niketkumar, Jain Shashank, Lin Senshang · Int J Pharm · 2016
PMID: 27633278Preclinical
Influence of electronic and formulation variables on transdermal iontophoresis of tacrine hydrochloride.
Patel Niketkumar, Jain Shashank, Madan Parshotam et al. · Pharm Dev Technol · 2015
PMID: 24467234Preclinical
[Synthesis of prodrugs of tacrine hydrochloride and evaluation of the stability and biodistribution in mice].
Jiang Yu, Zhang Yan, Zhang Zhi-rong · Yao Xue Xue Bao · 2003
PMID: 15040096Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Tacrine hydrochloride (substance)
SNOMED CT
108495009
UMLS CUI
C0771182

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.