Substance / Medication

Tafasitamab

Overview

Active Ingredient
tafasitamab
RxNorm CUI
2387211

Indications

MONJUVI, in combination with lenalidomide, is indicated for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) not otherwise specified, including DLBCL arising from low grade lymphoma, and who are not eligible for autologous stem cell transplant (ASCT). Clinical Studies (14) [see] This indication is approved under accelerated approval based on overall response rate. Continued approval for this indication may be contingent upon verification and descr

Labeler: Incyte CorporationUpdated: 2026-02-02T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

None.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Safety and efficacy of tafasitamab with or without lenalidomide added to first-line R-CHOP for DLBCL: the phase 1b First-MIND study.
Belada David, Kopeckova Katerina, Bergua Burgues Juan Miguel et al. · Blood · 2023
PMID: 37369099RCTFull text (PMC)
TALOs, Fill the Gap: Tafasitamab and Lenalidomide in Diffuse Large B-Cell Lymphoma in the Real-Life Patient Journey.
Argnani Lisa, Pellegrini Cinzia, Annibali Ombretta et al. · Hematol Oncol · 2026
PMID: 41532360ObservationalFull text (PMC)
Tafasitamab plus lenalidomide as salvage therapy in diffuse large B-cell lymphoma: real-world experience from GELTAMO.
Gutierrez Antonio, Zeberio Izaskun, Peñalver Francisco Javier et al. · Blood Adv · 2025
PMID: 40668613ObservationalFull text (PMC)
Clinical benefit of tafasitamab plus lenalidomide in relapsed or refractory diffuse large B-cell lymphoma: real-world data from the EarlyMIND study.
Brisou Gabriel, Paillassa Jérôme, Bernard Sophie et al. · Haematologica · 2025
PMID: 40371897ObservationalFull text (PMC)
Tafasitamab and lenalidomide in large B-cell lymphoma: real-world outcomes in a multicenter retrospective study.
Qualls David A, Lambert Nicholas, Caimi Paolo F et al. · Blood · 2023
PMID: 37738563ObservationalFull text (PMC)
Anti-CD19 antibody tafasitamab therapy for relapsed or refractory diffuse large B-cell lymphoma: a case series.
You Jianhua, Chen Wenting, Yan Zixun et al. · Anticancer Drugs · 2026
PMID: 41176775Case Report
Tafasitamab in refractory diffuse large B-cell lymphoma with neurolymphomatosis.
Mendes João Ricardo Belo Freitas, Couleur Laurine, Manca Chloe et al. · Ann Hematol · 2025
PMID: 39934427Case ReportFull text (PMC)
Tafasitamab and lenalidomide for relapsed/refractory diffuse large B-cell lymphoma in a patient on chronic intermittent hemodialysis.
Moore Donald C, Eagers Keren A, Janes Amanda et al. · J Oncol Pharm Pract · 2023
PMID: 35585701Case Report

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Tafasitamab (substance)
SNOMED CT
896700009
UMLS CUI
C5139916
RxNorm CUI
2387211
Labeler
Incyte Corporation

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.