Substance / Medication

Tinidazole

Overview

Active Ingredient
tinidazole
RxNorm CUI
10612
Labeler: Edenbridge Pharmaceuticals LLC.Updated: 2025-12-17T00:00:00.000ZFull label on DailyMed

Boxed Warning

FDA Black Box Warning

Nonclinical Toxicology (13.1 Indications and Usage Warnings and Precautions(5.1) 1.1 1.2 1.3 Carcinogenicity has been seen in mice and rats treated chronically with metronidazole, another nitroimidazole agent [see)]. Although such data have not been reported for tinidazole, the two drugs are structu

Contraindications

When this intervention should not be used

The use of tinidazole is contraindicated: Adverse Reactions (6.1 6.2) see, In patients with a previous history of hypersensitivity to tinidazole or other nitroimidazole derivatives. Reported reactions have ranged in severity from urticaria to Stevens-Johnson syndrome []. Adverse Reactions (6.2) In p

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

5 trials linked to this intervention

5
Total Trials
0
Recruiting
1
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Tinidazole vs metronidazole for the treatment of bacterial vaginosis: a systematic review and meta-analysis.
Sobral Milene Vitória Sampaio, Soares Victor Gonçalves, Moreira João Lucas de Magalhães Leal et al. · Arch Gynecol Obstet · 2025
PMID: 39969560Meta-AnalysisFull text (PMC)
Doxycycline vs levofloxacin combined with tinidazole for treating chronic endometritis: a randomized controlled trial.
Liu Yue, Zhao Zijun, Jiang Xiaorui et al. · Am J Obstet Gynecol · 2026
PMID: 40754174RCT
Triangular test design to evaluate tinidazole in the prevention of Plasmodium vivax relapse.
Macareo Louis, Lwin Khin Maung, Cheah Phaik Yeong et al. · Malar J · 2013
PMID: 23718705RCTFull text (PMC)
Pharmacokinetics of Tinidazole in Chinese subjects: comparison of Mongolian, Korean, Hui, Uighur and Han nationalities.
Chang Xin-Yu, Guo Tao, Xia Dong-Ya · J Pharm Pharm Sci · 2009
PMID: 19732495RCT
The treatment of giardiasis in children: single-dose tinidazole compared with 3 days of nitazoxanide.
Escobedo A A, Alvarez G, González M E et al. · Ann Trop Med Parasitol · 2008
PMID: 18348774RCT
Combined ciprofloxacin and tinidazole therapy in the treatment of chronic refractory pouchitis.
Shen Bo, Fazio Victor W, Remzi Feza H et al. · Dis Colon Rectum · 2007
PMID: 17279300RCT
A randomized, controlled, open-label trial of a single day of mebendazole versus a single dose of tinidazole in the treatment of giardiasis in children.
Cañete Roberto, Escobedo Angel A, González Maria Elena et al. · Curr Med Res Opin · 2006
PMID: 17076973RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Tinidazole (substance)
SNOMED CT
395907001
UMLS CUI
C0040263
RxNorm CUI
10612
Labeler
Edenbridge Pharmaceuticals LLC.

Clinical Data

This intervention maps to 9 entities in the Healos knowledge graph.

9
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
5
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.