Substance / Medication

Tiotropium bromide

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

18 trials linked to this intervention

18
Total Trials
2
Recruiting
5
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Intermittent Tiotropium Bromide for Episodic Wheezing: A Randomized Trial.
Kotaniemi-Syrjänen Anne, Klemola Timo, Koponen Petri et al. · Pediatrics · 2022
PMID: 35942814RCT
Tiotropium Bromide Attenuates Mucus Hypersecretion in Patients with Stable Chronic Obstructive Pulmonary Disease.
Yu Suyun, Zhang Caili, Yan Zhijun et al. · Comput Math Methods Med · 2021
PMID: 34650619RCTFull text (PMC)
Therapeutic Effects of a Long-Acting Cholinergic Receptor Blocker, Tiotropium Bromide, on Asthma.
Zhang Li, Huang Guangyin, Jin Long et al. · Med Sci Monit · 2018
PMID: 29446377RCTFull text (PMC)
Pharmacokinetic Bioequivalence of Two Inhaled Tiotropium Bromide Formulations in Healthy Volunteers.
Algorta Jaime, Andrade Laura, Medina Marta et al. · Clin Drug Investig · 2016
PMID: 27470430RCTFull text (PMC)
[The efficacy and safety of low-dose tiotropium bromide inhaled via Respimat® in patients with chronic obstructive pulmonary disease].
Ma Jinfang, Zhou Zhimin, Tang Yan et al. · Zhonghua Nei Ke Za Zhi · 2014
PMID: 25623564RCT
Effects of formoterol and tiotropium bromide on mucus clearance in patients with COPD.
Meyer Thomas, Reitmeir Peter, Brand Peter et al. · Respir Med · 2011
PMID: 21397483RCT
[The curative effect of Fluticasone Salmeterol combined with Tiotropium Bromide for silicosis].
Zhang Zhuo-ran, Jin Wei · Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi · 2011
PMID: 22468303RCT
Paradoxical trough effects of triple therapy with budesonide/formoterol and tiotropium bromide on pulmonary function outcomes in COPD.
Williamson Peter A, Short Philip M, Clearie Karine L et al. · Chest · 2010
PMID: 20418370RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Tiotropium bromide (substance)
SNOMED CT
425812008
UMLS CUI
C1306772

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
18
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.

Tiotropium bromide — Conditions, Biomarkers & Specialists | Healos | Ltrl