Substance / Medication

Tolnaftate

Overview

Active Ingredient
tolnaftate
RxNorm CUI
10637

Indications

Mycozyl HC™ Cream Gel is indicated for treatment of fungal infection of the skin and for the relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Labeler: PURETEK CORPORATIONUpdated: 2024-03-14T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

This product is contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Novel spectral manipulations for determinations of Tolnaftate along with related toxic compounds: Drug profiling and a comparative study.
Emam Raghda A, Abdelrahman Maha M, Abdelaleem Eglal A et al. · Spectrochim Acta A Mol Biomol Spectrosc · 2019
PMID: 31284238Observational
Nonplanar property study of antifungal agent tolnaftate-spectroscopic approach.
Dhas D Arul, Joe I Hubert, Roy S D D et al. · Spectrochim Acta A Mol Biomol Spectrosc · 2011
PMID: 21565546Other
Tolnaftate inhibits ergosterol production and impacts cell viability of Leishmania sp.
Yamamoto Eduardo Seiji, de Jesus Jéssica Adriana, Bezerra-Souza Adriana et al. · Bioorg Chem · 2020
PMID: 32653607Preclinical
Enhancement of the topical tolnaftate delivery for the treatment of tinea pedis via provesicular gel systems.
AbouSamra Mona Mahmoud, Salama Alaa Hamed · J Liposome Res · 2017
PMID: 27666873Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Tolnaftate (substance)
SNOMED CT
387204001
UMLS CUI
C0040379
RxNorm CUI
10637
Labeler
PURETEK CORPORATION

Clinical Data

This intervention maps to 2 entities in the Ltrl knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.