Substance / Medication

Trypsin

Overview

Active Ingredient
trypsin
RxNorm CUI
10890

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

23 trials linked to this intervention

23
Total Trials
1
Recruiting
6
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Patient-reported outcome measures for use in patients with alpha-1-antitrypsin deficiency: results of a systematic selection process.
Müller Karolina, Vogl Louisa, Knüttel Helge et al. · BMJ Open Respir Res · 2025
PMID: 41314659Meta-AnalysisFull text (PMC)
Alpha-1 antitrypsin deficiency and granulomatosis with polyangiitis: a systematic review and meta-analysis.
Alluhibi Reem, Baradwaaj Shashank, Heyer-Chauhan Nina et al. · Eur Respir Rev · 2025
PMID: 41125409Meta-AnalysisFull text (PMC)
Applications of Artificial Intelligence in Alpha-1 Antitrypsin Deficiency: A Systematic Review from a Respiratory Medicine Perspective.
Casal-Guisande Manuel, Villar-Aguilar Laura, Fernández-Villar Alberto et al. · Medicina (Kaunas) · 2025
PMID: 41155753Meta-AnalysisFull text (PMC)
Rare variants in alpha 1 antitrypsin deficiency: a systematic literature review.
Ferrarotti Ilaria, Wencker Marion, Chorostowska-Wynimko Joanna · Orphanet J Rare Dis · 2024
PMID: 38388492Meta-AnalysisFull text (PMC)
Meta-analysis: Prevalence of significant or advanced fibrosis in adults with alpha-1-antitrypsin deficiency.
Huang Daniel Q, Chan Kai En, Tan Caitlyn et al. · Aliment Pharmacol Ther · 2023
PMID: 37089038Meta-AnalysisFull text (PMC)
A meta-analysis for assessing the contributions of trypsin and chymotrypsin as the two major endoproteases in protein hydrolysis in fish intestine.
Solovyev Mikhail, Kashinskaya Elena, Gisbert Enric · Comp Biochem Physiol A Mol Integr Physiol · 2023
PMID: 36682676Meta-Analysis
Trypsinogen (PRSS1 and PRSS2) gene dosage correlates with pancreatitis risk across genetic and transgenic studies: a systematic review and re-analysis.
Zou Wen-Bin, Cooper David N, Masson Emmanuelle et al. · Hum Genet · 2022
PMID: 35089416Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Trypsin (substance)
SNOMED CT
66124006
UMLS CUI
C0041236
RxNorm CUI
10890

Clinical Data

This intervention maps to 2 entities in the Ltrl knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
23
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.