Aldosterone and Plasma Renin Test with Ratio

Aldosterone is a hormone produced by your adrenal glands that regulates salt and water balance, which directly affects blood pressure. This test measures aldosterone levels in your blood. Elevated aldosterone can cause high blood pressure and low potassium levels, potentially indicating primary aldosteronism (Conn's syndrome) or secondary hyperaldosteronism from kidney disease or heart failure. Low aldosterone may suggest adrenal insufficiency.

This panel measures two hormones—aldosterone and renin—that work together to regulate blood pressure and fluid balance. Aldosterone is produced by the adrenal glands and increases sodium and water retention; renin is produced by the kidneys and activates this system. Abnormal ratios may indicate primary hyperaldosteronism (excess aldosterone), secondary hyperaldosteronism (from kidney or heart disease), or adrenal insufficiency. This test is typically ordered when evaluating resistant hypertension, persistent low potassium, or suspected adrenal disorders.

This test measures the ratio of aldosterone to renin, two hormones that regulate blood pressure and electrolyte balance. Aldosterone is produced by the adrenal glands, while renin is produced by the kidneys. An elevated aldosterone-to-renin ratio suggests primary hyperaldosteronism, a condition causing high blood pressure and potassium loss. This test is typically performed when someone has hypertension resistant to medication or unexplained low potassium. Identifying hyperaldosteronism is important because it requires specific treatment approaches.