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THOMAS GERKEN, MD
MD
Anesthesiology Physician
NPI: 1033187422Individual
Specialties, Licenses & Credentials
Research & Publications (20)
Conservation of peptide acceptor preferences between Drosophila and mammalian polypeptide-GalNAc transferase ortholog pairs.
PMID 18669915·Glycobiology·2008
4-observational
Identification of common and unique peptide substrate preferences for the UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferases T1 and T2 derived from oriented random peptide substrates.
PMID 16912039·J Biol Chem·2006
4-observational
Role of peptide sequence and neighboring residue glycosylation on the substrate specificity of the uridine 5'-diphosphate-alpha-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyl transferases T1 and T2: kinetic modeling of the porcine and canine submaxillary gland mucin tandem repeats.
PMID 15274643·Biochemistry·2004
4-observational
Kinetic modeling confirms the biosynthesis of mucin core 1 (beta-Gal(1-3) alpha-GalNAc-O-Ser/Thr) O-glycan structures are modulated by neighboring glycosylation effects.
PMID 15065856·Biochemistry·2004
7-preclinical
Mucin core O-glycosylation is modulated by neighboring residue glycosylation status. Kinetic modeling of the site-specific glycosylation of the apo-porcine submaxillary mucin tandem repeat by UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases T1 and T2.
PMID 12397077·J Biol Chem·2002
7-preclinical
Determination of the site-specific oligosaccharide distribution of the O-glycans attached to the porcine submaxillary mucin tandem repeat. Further evidence for the modulation of O-glycans side chain structures by peptide sequence.
PMID 11777921·J Biol Chem·2002
7-preclinical
A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene.
PMID 19680540·PLoS Genet·2009
7-preclinical
Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers.
PMID 19617566·Proc Natl Acad Sci U S A·2009
7-preclinical
Glycopeptide-preferring polypeptide GalNAc transferase 10 (ppGalNAc T10), involved in mucin-type O-glycosylation, has a unique GalNAc-O-Ser/Thr-binding site in its catalytic domain not found in ppGalNAc T1 or T2.
PMID 19460755·J Biol Chem·2009
7-preclinical
Single-molecule pair studies of the interactions of the alpha-GalNAc (Tn-antigen) form of porcine submaxillary mucin with soybean agglutinin.
PMID 19384982·Biopolymers·2009
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 5901 MONCLOVA RD
MAUMEE, OH 43537 - Phone
- (419) 897-8370
Quick Facts
- NPI
- 1033187422
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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