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MARY COWART, M.D.
M.D.
Diagnostic Radiology Physician
NPI: 1124009840Individual
Specialties, Licenses & Credentials
Diagnostic Radiology PhysicianPrimary
Radiology — Diagnostic Radiology
Code: 2085R0202X
07643(MS)
Research & Publications (20)
In vitro and in vivo characterization of A-940894: a potent histamine H4 receptor antagonist with anti-inflammatory properties.
PMID 19413570·Br J Pharmacol·2009
7-preclinical
Use of the H3 receptor antagonist radioligand [3H]-A-349821 to reveal in vivo receptor occupancy of cognition enhancing H3 receptor antagonists.
PMID 19413577·Br J Pharmacol·2009
4-observational
Design of a new histamine H3 receptor antagonist chemotype: (3aR,6aR)-5-alkyl-1-aryl-octahydropyrrolo[3,4-b]pyrroles, synthesis, and structure-activity relationships.
PMID 19588934·J Med Chem·2009
7-preclinical
The histamine H3 receptor: an attractive target for the treatment of cognitive disorders.
PMID 18469850·Br J Pharmacol·2008
6-review
Structure-activity studies on a series of a 2-aminopyrimidine-containing histamine H4 receptor ligands.
PMID 18811133·J Med Chem·2008
7-preclinical
The alkaloid conessine and analogues as potent histamine H3 receptor antagonists.
PMID 18683917·J Med Chem·2008
7-preclinical
In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists: trends across multiple chemical series.
PMID 18077160·Bioorg Med Chem Lett·2008
7-preclinical
Rotationally constrained 2,4-diamino-5,6-disubstituted pyrimidines: a new class of histamine H4 receptor antagonists with improved druglikeness and in vivo efficacy in pain and inflammation models.
PMID 18817367·J Med Chem·2008
7-preclinical
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
PMID 18983139·J Med Chem·2008
7-preclinical
A robust and high-capacity [(35)S]GTPgammaS binding assay for determining antagonist and inverse agonist pharmacological parameters of histamine H(3) receptor ligands.
PMID 18593375·Assay Drug Dev Technol·2008
8-other
Minimization of potential hERG liability in histamine H3 receptor antagonists.
PMID 18345496·Inflamm Res·2008
7-preclinical
Synthesis, potency, and in vivo profiles of quinoline containing histamine H3 receptor inverse agonists.
PMID 17918921·J Med Chem·2007
7-preclinical
Novel heterocyclic-substituted benzofuran histamine H3 receptor antagonists: in vitro properties, drug-likeness, and behavioral activity.
PMID 17371699·Biochem Pharmacol·2007
7-preclinical
A new family of histamine H3 receptor antagonists based on a natural product: discovery, SAR, and properties of the series.
PMID 17806176·Inflamm Res·2007
7-preclinical
An 80-amino acid deletion in the third intracellular loop of a naturally occurring human histamine H3 isoform confers pharmacological differences and constitutive activity.
PMID 17855474·J Pharmacol Exp Ther·2007
7-preclinical
4-[6-(2-Aminoethyl)naphthalen-2-yl]benzonitriles are potent histamine H3 receptor antagonists with high CNS penetration.
PMID 17169555·Bioorg Med Chem Lett·2007
7-preclinical
Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction.
PMID 17149874·J Med Chem·2006
7-preclinical
Crystal structures of human adenosine kinase inhibitor complexes reveal two distinct binding modes.
PMID 17154503·J Med Chem·2006
4-observational
Fluorescent benzofuran histamine H(3) receptor antagonists with sub-nanomolar potency.
PMID 16705379·Inflamm Res·2006
8-other
Histamine H3 receptor antagonists: preclinical promise for treating obesity and cognitive disorders.
PMID 16565470·Mol Interv·2006
6-review
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1203 24TH AVE
MERIDIAN, MS 39301 - Phone
- (601) 693-5862
Quick Facts
- NPI
- 1124009840
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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