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DARRYL HEIN, M.D.
M.D.
Internal Medicine Physician
NPI: 1124077227IndividualAccepts Medicare
Specialties, Licenses & Credentials
Internal Medicine PhysicianPrimary
Internal Medicine
Code: 207R00000X
G77097(CA)
Education
UNIVERSITY OF CALIFORNIA, GEFFEN SCHOOL OF MEDICINE
Class of 1992
Research & Publications (20)
N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine.
PMID 19379125·Expert Opin Drug Metab Toxicol·2009
6-review
Tissue distribution of N-acetyltransferase 1 and 2 catalyzing the N-acetylation of 4-aminobiphenyl and O-acetylation of N-hydroxy-4-aminobiphenyl in the congenic rapid and slow acetylator Syrian hamster.
PMID 16482518·Mol Carcinog·2006
7-preclinical
Prostate expression of N-acetyltransferase 1 (NAT1) and 2 (NAT2) in rapid and slow acetylator congenic Syrian hamster.
PMID 12618593·Pharmacogenetics·2003
7-preclinical
Investigation of the effect of the extraction phase geometry on the performance of automated solid-phase microextraction.
PMID 19413335·Anal Chem·2009
8-other
4-Aminobiphenyl downregulation of NAT2 acetylator genotype-dependent N- and O-acetylation of aromatic and heterocyclic amine carcinogens in primary mammary epithelial cell cultures from rapid and slow acetylator rats.
PMID 18842621·Toxicol Sci·2009
7-preclinical
The impact of NAT2 acetylator genotype on mutagenesis and DNA adducts from 2-amino-9H-pyrido[2,3-b]indole.
PMID 19243127·Chem Res Toxicol·2009
7-preclinical
Effects of dietary factors and the NAT2 acetylator status on gastric cancer in Koreans.
PMID 19350634·Int J Cancer·2009
4-observational
Effect of N-acetyltransferase 2 polymorphism on tumor target tissue DNA adduct levels in rapid and slow acetylator congenic rats administered 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline.
PMID 19666988·Drug Metab Dispos·2009
4-observational
Manganese superoxide dismutase V16A single-nucleotide polymorphism in the mitochondrial targeting sequence is associated with reduced enzymatic activity in cryopreserved human hepatocytes.
PMID 18821846·DNA Cell Biol·2009
8-other
A flexible route to chiral 2-endo-substituted 9-oxabispidines and their application in the enantioselective oxidation of secondary alcohols.
PMID 19086891·J Org Chem·2009
8-other
Skin metabolism of aminophenols: human keratinocytes as a suitable in vitro model to qualitatively predict the dermal transformation of 4-amino-2-hydroxytoluene in vivo.
PMID 19100279·Toxicol Appl Pharmacol·2009
7-preclinical
Role of human CYP1A1 and NAT2 in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mutagenicity and DNA adducts.
PMID 19301197·Xenobiotica·2009
7-preclinical
Inactivation of GSK-3beta by metallothionein prevents diabetes-related changes in cardiac energy metabolism, inflammation, nitrosative damage, and remodeling.
PMID 19324938·Diabetes·2009
7-preclinical
Multibed needle trap devices for on site sampling and preconcentration of volatile breath biomarkers.
PMID 19548667·Anal Chem·2009
7-preclinical
Para-phenylenediamine and allergic sensitization: risk modification by N-acetyltransferase 1 and 2 genotypes.
PMID 19663877·Br J Dermatol·2009
8-other
Differences between human slow N-acetyltransferase 2 alleles in levels of 4-aminobiphenyl-induced DNA adducts and mutations.
PMID 19682468·Mutat Res·2009
7-preclinical
Development and application of a needle trap device for time-weighted average diffusive sampling.
PMID 18763805·Anal Chem·2008
8-other
Mouse arylamine N-acetyltransferase 2 (Nat2) expression during embryogenesis: a potential marker for the developing neuroendocrine system.
PMID 17896208·Biomarkers·2008
7-preclinical
Metallothionein suppresses angiotensin II-induced nicotinamide adenine dinucleotide phosphate oxidase activation, nitrosative stress, apoptosis, and pathological remodeling in the diabetic heart.
PMID 18702970·J Am Coll Cardiol·2008
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 15215 NATIONAL AVE, SUITE 200
LOS GATOS, CA 95032 - Phone
- (408) 358-1841
Quick Facts
- NPI
- 1124077227
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 1
- Years in Practice
- 34
- Publications
- 20
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