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MARGARET LIBONATI, M.D
M.D
Allergy & Immunology Physician
NPI: 1124364294Individual
Specialties, Licenses & Credentials
Allergy & Immunology PhysicianPrimary
Allergy & Immunology
Code: 207K00000X
MD008950E(PA)
Research & Publications (20)
A novel biological actions acquired by ribonuclease through oligomerization.
PMID 18673285·Curr Pharm Biotechnol·2008
6-review
Oligomerization of bovine ribonuclease A: structural and functional features of its multimers.
PMID 15104538·Biochem J·2004
6-review
Degradation of double-stranded RNA by mammalian pancreatic-type ribonucleases.
PMID 11582780·Methods Enzymol·2001
7-preclinical
Carbodiimide EDC induces cross-links that stabilize RNase A C-dimer against dissociation: EDC adducts can affect protein net charge, conformation, and activity.
PMID 19606852·Bioconjug Chem·2009
8-other
Oligomerization of ribonuclease A under reducing conditions.
PMID 18261475·Biochim Biophys Acta·2008
7-preclinical
Natalizumab therapy for moderate to severe Crohn disease in adolescents.
PMID 17255829·J Pediatr Gastroenterol Nutr·2007
3-trial
Increase of RNase a N-terminus polarity or C-terminus apolarity changes the two domains' propensity to swap and form the two dimeric conformers of the protein.
PMID 16953565·Biochemistry·2006
4-observational
Some biological actions of PEG-conjugated RNase A oligomers.
PMID 16416018·Neoplasma·2006
7-preclinical
Formation, structure, and dissociation of the ribonuclease S three-dimensional domain-swapped dimer.
PMID 16415350·J Biol Chem·2006
7-preclinical
Three-dimensional domain-swapped oligomers of ribonuclease A: identification of a fifth tetramer, pentamers and hexamers, and detection of trace heptameric, octameric and nonameric species.
PMID 16310422·Biochim Biophys Acta·2006
7-preclinical
An open-label safety and drug interaction study of natalizumab (Antegren) in combination with interferon-beta (Avonex) in patients with multiple sclerosis.
PMID 15471366·Mult Scler·2004
3-trial
Oligomerization of ribonuclease A: two novel three-dimensional domain-swapped tetramers.
PMID 15218036·J Biol Chem·2004
7-preclinical
Randomized multicenter trial of natalizumab in acute MS relapses: clinical and MRI effects.
PMID 15184611·Neurology·2004
3-trial
Glycosylation and specific deamidation of ribonuclease B affect the formation of three-dimensional domain-swapped oligomers.
PMID 12966091·J Biol Chem·2003
8-other
Antitumor activity and other biological actions of oligomers of ribonuclease A.
PMID 12697760·J Biol Chem·2003
7-preclinical
Thermal aggregation of ribonuclease A. A contribution to the understanding of the role of 3D domain swapping in protein aggregation.
PMID 12533538·J Biol Chem·2003
7-preclinical
A controlled trial of natalizumab for relapsing multiple sclerosis.
PMID 12510038·N Engl J Med·2003
3-trial
Structural properties of trimers and tetramers of ribonuclease A.
PMID 11567093·Protein Sci·2001
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 7277 BAUSCH ROAD
NEW TRIPOLI, PA 18066 - Phone
- (610) 298-2382
Quick Facts
- NPI
- 1124364294
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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