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DAVID LEISHMAN, MD
MD
Surgery Physician
NPI: 1134682834Individual
Specialties, Licenses & Credentials
Research & Publications (15)
Overcoming hERG affinity in the discovery of maraviroc; a CCR5 antagonist for the treatment of HIV.
PMID 18782009·Curr Top Med Chem·2008
8-other
International Life Sciences Institute (Health and Environmental Sciences Institute, HESI) initiative on moving towards better predictors of drug-induced torsades de pointes.
PMID 18663380·Br J Pharmacol·2008
7-preclinical
Inhibition of the HERG potassium channel by the tricyclic antidepressant doxepin.
PMID 17560554·Biochem Pharmacol·2007
7-preclinical
hERG K+ channel blockade by the antipsychotic drug thioridazine: An obligatory role for the S6 helix residue F656.
PMID 17056009·Biochem Biophys Res Commun·2006
8-other
Overcoming HERG affinity in the discovery of the CCR5 antagonist maraviroc.
PMID 16782336·Bioorg Med Chem Lett·2006
8-other
Mechanism of hERG K+ channel blockade by the fluoroquinolone antibiotic moxifloxacin.
PMID 16474415·Br J Pharmacol·2006
8-other
Erythromycin block of the HERG K+ channel: accessibility to F656 and Y652.
PMID 16446155·Biochem Biophys Res Commun·2006
8-other
Drug binding interactions in the inner cavity of HERG channels: molecular insights from structure-activity relationships of clofilium and ibutilide analogs.
PMID 16291873·Mol Pharmacol·2006
7-preclinical
A pharmacokinetic-pharmacodynamic model for the quantitative prediction of dofetilide clinical QT prolongation from human ether-a-go-go-related gene current inhibition data.
PMID 15961988·Clin Pharmacol Ther·2005
8-other
Structural determinants of HERG channel block by clofilium and ibutilide.
PMID 15266014·Mol Pharmacol·2004
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
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Contact & Hours
- Address
- 420 DELAWARE ST SE
MINNEAPOLIS, MN 55455 - Phone
- (612) 625-6483
Quick Facts
- NPI
- 1134682834
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 3
- Locations
- 3
- Publications
- 15
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