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CHARLES ISHAM, MD

MD

Internal Medicine Physician

NPI: 1184669269Individual

Specialties, Licenses & Credentials

Internal Medicine PhysicianPrimary

Internal Medicine

Code: 207R00000X

13405(TN)

Research & Publications (5)

The anticancer agent chaetocin is a competitive substrate and inhibitor of thioredoxin reductase.
PMID 18999987·Antioxid Redox Signal·2009
8-other
Chaetocin: a promising new antimyeloma agent with in vitro and in vivo activity mediated via imposition of oxidative stress.
PMID 17090648·Blood·2007
7-preclinical
Flavopiridol in patients with relapsed or refractory multiple myeloma: a phase 2 trial with clinical and pharmacodynamic end-points.
PMID 16503551·Haematologica·2006
3-trial
Flavopiridol disrupts STAT3/DNA interactions, attenuates STAT3-directed transcription, and combines with the Jak kinase inhibitor AG490 to achieve cytotoxic synergy.
PMID 16432172·Mol Cancer Ther·2006
8-other
Phase 1 trial of flavopiridol combined with cisplatin or carboplatin in patients with advanced malignancies with the assessment of pharmacokinetic and pharmacodynamic end points.
PMID 16115936·Clin Cancer Res·2005
3-trial

Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.

Contact & Hours

Address
163 PERKINS LN
JACKSBORO, TN 37757

Quick Facts

NPI
1184669269
Entity Type
Individual
Gender
Male
Medicare
Not confirmed
Specialties
1
Locations
1
Publications
5

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