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TIMOTHY HIRST, MD
MD
Family Medicine Physician
NPI: 1215937750Individual
Specialties, Licenses & Credentials
Family Medicine PhysicianPrimary
Family Medicine
Code: 207Q00000X
35037750(OH)
Research & Publications (20)
Bystander protein protects potential vaccine-targeting ligands against intestinal proteolysis.
PMID 19332091·J Control Release·2009
7-preclinical
Phage-display derived single-chain fragment variable (scFv) antibodies recognizing conformational epitopes of Escherichia coli heat-labile enterotoxin B-subunit.
PMID 18786540·J Immunol Methods·2008
7-preclinical
Inhibition of Escherichia coli heat-labile enterotoxin B subunit pentamer (EtxB5) assembly in vitro using monoclonal antibodies.
PMID 17038315·J Biol Chem·2006
7-preclinical
Defective Vav expression and impaired F-actin reorganization in a subset of patients with common variable immunodeficiency characterized by T-cell defects.
PMID 15817684·Blood·2005
8-other
The B subunit of Escherichia coli heat-labile enterotoxin induces both caspase-dependent and -independent cell death pathways in CD8+ T cells.
PMID 15385486·Infect Immun·2004
7-preclinical
Trafficking of exogenous peptides into proteasome-dependent major histocompatibility complex class I pathway following enterotoxin B subunit-mediated delivery.
PMID 15342647·J Biol Chem·2004
7-preclinical
Recombinant Streptococcus equi proteins protect mice in challenge experiments and induce immune response in horses.
PMID 15155624·Infect Immun·2004
7-preclinical
Ganglioside GM1 binding toxins and human neuropathy-associated IgM antibodies differentially promote neuritogenesis in a PC12 assay.
PMID 14630342·Neurosci Res·2003
4-observational
Selective induction of CD8+CD4- thymocyte apoptosis mediated by the B-subunit of Escherichia coli heat-labile enterotoxin.
PMID 12853160·Immunol Lett·2003
7-preclinical
Protection against recurrent ocular herpes simplex virus type 1 disease after therapeutic vaccination of latently infected mice.
PMID 12767989·J Virol·2003
7-preclinical
The B subunit of Escherichia coli heat-labile enterotoxin enhances CD8+ cytotoxic-T-lymphocyte killing of Epstein-Barr virus-infected cell lines.
PMID 12634387·J Virol·2003
8-other
Mutant Escherichia coli heat-labile toxin B subunit that separates toxoid-mediated signaling and immunomodulatory action from trafficking and delivery functions.
PMID 12595472·Infect Immun·2003
7-preclinical
CD8+ T cell apoptosis induced by Escherichia coli heat-labile enterotoxin B subunit occurs via a novel pathway involving NF-kappaB-dependent caspase activation.
PMID 12115657·Eur J Immunol·2002
7-preclinical
Escherichia coli heat-labile enterotoxin B subunit prevents autoimmune arthritis through induction of regulatory CD4+ T cells.
PMID 12115200·Arthritis Rheum·2002
7-preclinical
Modulation of human monocytes by Escherichia coli heat-labile enterotoxin B-subunit; altered cytokine production and its functional consequences.
PMID 12100719·Immunology·2002
8-other
Expression of chemokine receptors in the feline reproductive tract and large intestine.
PMID 12056777·J Comp Pathol·2002
7-preclinical
Enhanced delivery of exogenous peptides into the class I antigen processing and presentation pathway.
PMID 12011020·Infect Immun·2002
7-preclinical
Bacterial toxins as versatile delivery vehicles.
PMID 11926133·Curr Opin Drug Discov Devel·2002
6-review
New insights into the structure-function relationships and therapeutic applications of cholera-like enterotoxins.
PMID 11890554·Int J Med Microbiol·2002
6-review
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 345 N 15TH ST
SEBRING, OH 44672 - Phone
- (330) 821-2592
Quick Facts
- NPI
- 1215937750
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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