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JOHN BEUMER, M.D.
M.D.
Pediatrics Physician
NPI: 1215981964Individual
Specialties, Licenses & Credentials
Pediatrics PhysicianPrimary
Pediatrics
Code: 208000000X
MD00041376(WA)
Research & Publications (20)
Disposition and toxicity of trabectedin (ET-743) in wild-type and mdr1 gene (P-gp) knock-out mice.
PMID 19238326·Invest New Drugs·2010
7-preclinical
Sulforaphane inhibits prostate carcinogenesis and pulmonary metastasis in TRAMP mice in association with increased cytotoxicity of natural killer cells.
PMID 19223537·Cancer Res·2009
7-preclinical
Evaluation of human plasma protein binding of trabectedin (Yondelis, ET-743).
PMID 19149499·Curr Clin Pharmacol·2009
8-other
Disposition of temozolomide in a patient with glioblastoma multiforme after gastric bypass surgery.
PMID 19125222·J Neurooncol·2009
5-case
A high-performance liquid chromatography-mass spectrometry assay for quantitation of the tyrosine kinase inhibitor nilotinib in human plasma and serum.
PMID 19493708·J Chromatogr B Analyt Technol Biomed Life Sci·2009
4-observational
Phase I pharmacokinetic study of the vascular endothelial growth factor receptor tyrosine kinase inhibitor vatalanib (PTK787) plus imatinib and hydroxyurea for malignant glioma.
PMID 19248046·Cancer·2009
3-trial
Modulation of gemcitabine (2',2'-difluoro-2'-deoxycytidine) pharmacokinetics, metabolism, and bioavailability in mice by 3,4,5,6-tetrahydrouridine.
PMID 18519786·Clin Cancer Res·2008
7-preclinical
Liquid chromatography-mass spectrometric assay for quantitation of the short-chain fatty acid, 2,2-dimethylbutyrate (NSC 741804), in rat plasma.
PMID 18155649·J Chromatogr B Analyt Technol Biomed Life Sci·2008
4-observational
Quantitation of 5-fluorouracil (5-FU) in human plasma by liquid chromatography/electrospray ionization tandem mass spectrometry.
PMID 18085512·Rapid Commun Mass Spectrom·2008
4-observational
Plasma pharmacokinetics and oral bioavailability of 3,4,5,6-tetrahydrouridine, a cytidine deaminase inhibitor, in mice.
PMID 18008070·Cancer Chemother Pharmacol·2008
7-preclinical
Concentrations of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine (FdCyd) and its cytotoxic metabolites in plasma of patients treated with FdCyd and tetrahydrouridine (THU).
PMID 17899082·Cancer Chemother Pharmacol·2008
3-trial
Liquid chromatography-mass spectrometric assay for the quantitation in human plasma of ABT-888, an orally available, small molecule inhibitor of poly(ADP-ribose) polymerase.
PMID 18692448·J Chromatogr B Analyt Technol Biomed Life Sci·2008
8-other
Metabolism of trabectedin (ET-743, Yondelis) in patients with advanced cancer.
PMID 16988825·Cancer Chemother Pharmacol·2007
8-other
Quantitative determination of the cytidine deaminase inhibitor tetrahydrouridine (THU) in mouse plasma by liquid chromatography/electrospray ionization tandem mass spectrometry.
PMID 17526067·Rapid Commun Mass Spectrom·2007
7-preclinical
Human mass balance study of the novel anticancer agent ixabepilone using accelerator mass spectrometry.
PMID 17347871·Invest New Drugs·2007
3-trial
Maxillofacial restoration after head and neck tumor therapy.
PMID 17319178·Compend Contin Educ Dent·2007
8-other
Trabectedin (ET-743, Yondelis) is a substrate for P-glycoprotein, but only high expression of P-glycoprotein confers the multidrug resistance phenotype.
PMID 16633714·Invest New Drugs·2007
7-preclinical
Use of osseointegrated implants in the restoration of head and neck defects.
PMID 17022295·J Calif Dent Assoc·2006
8-other
Pharmacokinetics, metabolism, and oral bioavailability of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine in mice.
PMID 17138702·Clin Cancer Res·2006
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 275 SE CABOT DR, SUITE B-102
OAK HARBOR, WA 98277 - Phone
- (360) 675-5555
Quick Facts
- NPI
- 1215981964
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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