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JAMES BURKE, M.D.
M.D.
Family Medicine Physician
NPI: 1225025679Individual
Specialties, Licenses & Credentials
Family Medicine PhysicianPrimary
Family Medicine
Code: 207Q00000X
19491(IA)
Research & Publications (20)
Targeting I kappa B kinase for the treatment of inflammatory and other disorders.
PMID 14579522·Curr Opin Drug Discov Devel·2003
6-review
BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice.
PMID 12403772·J Biol Chem·2003
7-preclinical
The catalytic subunits of IkappaB kinase, IKK-1 and IKK-2, contain non-equivalent active sites when expressed as homodimers.
PMID 12054687·Biochem Biophys Res Commun·2002
7-preclinical
Targeting phospholipase A2 for the treatment of inflammatory skin diseases.
PMID 11763156·Curr Opin Investig Drugs·2001
6-review
BMS-229724 is a tight-binding inhibitor of cytosolic phospholipase A2 that acts at the lipid/water interface and possesses anti-inflammatory activity in skin inflammation models.
PMID 11408565·J Pharmacol Exp Ther·2001
7-preclinical
Simvastatin impairs smad-3 phosphorylation and modulates transforming growth factor beta1-mediated activation of intestinal fibroblasts.
PMID 19358180·Br J Surg·2009
8-other
Null test of an off-axis parabolic mirror. II. Configuration with planar reference wave and spherical return surface.
PMID 19259160·Opt Express·2009
8-other
Location of inhibitors bound to group IVA phospholipase A2 determined by molecular dynamics and deuterium exchange mass spectrometry.
PMID 19459633·J Am Chem Soc·2009
8-other
Phospholipase A2 structure/function, mechanism, and signaling.
PMID 19011112·J Lipid Res·2009
6-review
Null test of an off-axis parabolic mirror. I. Configuration with spherical reference wave and flat return surface.
PMID 19259157·Opt Express·2009
8-other
Interaction of group IA phospholipase A2 with metal ions and phospholipid vesicles probed with deuterium exchange mass spectrometry.
PMID 18500818·Biochemistry·2008
7-preclinical
A phospholipid substrate molecule residing in the membrane surface mediates opening of the lid region in group IVA cytosolic phospholipase A2.
PMID 18753135·J Biol Chem·2008
7-preclinical
Transcriptomic analysis of intestinal fibrosis-associated gene expression in response to medical therapy in Crohn's disease.
PMID 18452219·Inflamm Bowel Dis·2008
8-other
Rapid and reliable reference sphere calibration for Fizeau interferometry.
PMID 18978912·Opt Lett·2008
8-other
A comparative study of risk factors and prognostic features between symptomatic and screen detected breast cancer.
PMID 17498912·Eur J Surg Oncol·2008
4-observational
Reciprocal relationships between parenting behavior and disruptive psychopathology from childhood through adolescence.
PMID 18286366·J Abnorm Child Psychol·2008
8-other
Inattention as a key predictor of tobacco use in adolescence.
PMID 17516758·J Abnorm Psychol·2007
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 3600 LINCOLN WAY
AMES, IA 50014 - Phone
- (515) 663-4892
Quick Facts
- NPI
- 1225025679
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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