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JULIO MENENDEZ, MD
MD
General Practice Physician
NPI: 1225259476Individual
Specialties, Licenses & Credentials
General Practice PhysicianPrimary
General Practice
Code: 208D00000X
7953(PR)
Research & Publications (20)
Orlistat: from antiobesity drug to anticancer agent in Her-2/neu (erbB-2)-overexpressing gastrointestinal tumors?
PMID 15734718·Exp Biol Med (Maywood)·2005
8-other
Antitumoral actions of the anti-obesity drug orlistat (XenicalTM) in breast cancer cells: blockade of cell cycle progression, promotion of apoptotic cell death and PEA3-mediated transcriptional repression of Her2/neu (erbB-2) oncogene.
PMID 15870086·Ann Oncol·2005
8-other
The antidiabetic drug metformin suppresses HER2 (erbB-2) oncoprotein overexpression via inhibition of the mTOR effector p70S6K1 in human breast carcinoma cells.
PMID 19106626·Cell Cycle·2009
8-other
Genome-wide inhibitory impact of the AMPK activator metformin on [kinesins, tubulins, histones, auroras and polo-like kinases] M-phase cell cycle genes in human breast cancer cells.
PMID 19372741·Cell Cycle·2009
8-other
Autophagy facilitates the development of breast cancer resistance to the anti-HER2 monoclonal antibody trastuzumab.
PMID 19606230·PLoS One·2009
8-other
The antidiabetic drug metformin: a pharmaceutical AMPK activator to overcome breast cancer resistance to HER2 inhibitors while decreasing risk of cardiomyopathy.
PMID 19153119·Ann Oncol·2009
8-other
The serine 2481-autophosphorylated form of mammalian Target Of Rapamycin (mTOR) is localized to midzone and midbody in dividing cancer cells.
PMID 19285014·Biochem Biophys Res Commun·2009
8-other
The petrosal nerves: anatomy, pathology, and surgical considerations.
PMID 19544297·Clin Anat·2009
6-review
Mitotic kinase dynamics of the active form of AMPK (phospho-AMPKalphaThr172) in human cancer cells.
PMID 19221486·Cell Cycle·2009
8-other
Fatty acid synthase: association with insulin resistance, type 2 diabetes, and cancer.
PMID 19181734·Clin Chem·2009
6-review
Extra-virgin olive oil polyphenols inhibit HER2 (erbB-2)-induced malignant transformation in human breast epithelial cells: relationship between the chemical structures of extra-virgin olive oil secoiridoids and lignans and their inhibitory activities on the tyrosine kinase activity of HER2.
PMID 19082476·Int J Oncol·2009
8-other
AMPK-sensed cellular energy state regulates the release of extracellular Fatty Acid Synthase.
PMID 19032940·Biochem Biophys Res Commun·2009
8-other
The active form of the metabolic sensor: AMP-activated protein kinase (AMPK) directly binds the mitotic apparatus and travels from centrosomes to the spindle midzone during mitosis and cytokinesis.
PMID 19556893·Cell Cycle·2009
7-preclinical
Analyzing effects of extra-virgin olive oil polyphenols on breast cancer-associated fatty acid synthase protein expression using reverse-phase protein microarrays.
PMID 18813848·Int J Mol Med·2008
8-other
The tyrosine kinase receptor HER2 (erbB-2): from oncogenesis to adipogenesis.
PMID 18814184·J Cell Biochem·2008
7-preclinical
tabAnti-HER2 (erbB-2) oncogene effects of phenolic compounds directly isolated from commercial Extra-Virgin Olive Oil (EVOO).
PMID 19094209·BMC Cancer·2008
8-other
Growth and molecular interactions of the anti-EGFR antibody cetuximab and the DNA cross-linking agent cisplatin in gefitinib-resistant MDA-MB-468 cells: new prospects in the treatment of triple-negative/basal-like breast cancer.
PMID 19020749·Int J Oncol·2008
8-other
Solid neuroendocrine breast carcinomas: incidence, clinico-pathological features and immunohistochemical profiling.
PMID 19020716·Oncol Rep·2008
8-other
Molecular-based synthetic approach to new group IV materials for high-efficiency, low-cost solar cells and Si-based optoelectronics.
PMID 19032100·J Am Chem Soc·2008
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- JOSE C BARBOSA STREET, #26
SALINAS, PR 00751 - Phone
- (787) 824-0706
Quick Facts
- NPI
- 1225259476
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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