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ERIC SIGEL, MD
MD
Pediatric Adolescent Medicine Physician
NPI: 1235214966Individual
Specialties, Licenses & Credentials
Pediatric Adolescent Medicine PhysicianPrimary
Pediatrics — Adolescent Medicine
Code: 2080A0000X
34143(CO)
Research & Publications (20)
The Xenopus oocyte: system for the study of functional expression and modulation of proteins.
PMID 15704243·Mol Nutr Food Res·2005
6-review
Mapping of the benzodiazepine recognition site on GABA(A) receptors.
PMID 12171574·Curr Top Med Chem·2002
6-review
Differential cross talk of ROD compounds with the benzodiazepine binding site.
PMID 11353808·Mol Pharmacol·2001
4-observational
Electrophysiological evidence for the coexistence of alpha1 and alpha6 subunits in a single functional GABA(A) receptor.
PMID 10820222·J Neurochem·2000
7-preclinical
Unanticipated structural and functional properties of delta-subunit-containing GABAA receptors.
PMID 19141615·J Biol Chem·2009
7-preclinical
Novel chloride channel mutations leading to mild myotonia among Chinese.
PMID 18579381·Neuromuscul Disord·2008
5-case
Covalent modification of GABAA receptor isoforms by a diazepam analogue provides evidence for a novel benzodiazepine binding site that prevents modulation by these drugs.
PMID 18643789·J Neurochem·2008
7-preclinical
The promiscuous role of the epsilon subunit in GABAA receptor biogenesis.
PMID 18206389·Mol Cell Neurosci·2008
7-preclinical
Replacement of histidine in position 105 in the α₅ subunit by cysteine stimulates zolpidem sensitivity of α₅β₂γ₂ GABA(A) receptors.
PMID 17953656·J Neurochem·2007
7-preclinical
Proximity-accelerated chemical coupling reaction in the benzodiazepine-binding site of gamma-aminobutyric acid type A receptors: superposition of different allosteric modulators.
PMID 17626010·J Biol Chem·2007
8-other
Two neighboring residues of loop A of the alpha1 subunit point towards the benzodiazepine binding site of GABAA receptors.
PMID 17854801·FEBS Lett·2007
8-other
A GABA(A) receptor of defined subunit composition and positioning: concatenation of five subunits.
PMID 16494876·FEBS Lett·2006
7-preclinical
Impact of subunit positioning on GABAA receptor function.
PMID 17052217·Biochem Soc Trans·2006
8-other
Benzodiazepines affect channel opening of GABA A receptors induced by either agonist binding site.
PMID 15657366·Mol Pharmacol·2005
7-preclinical
Conformational changes at benzodiazepine binding sites of GABA(A) receptors detected with a novel technique.
PMID 15686488·J Neurochem·2005
7-preclinical
Novel plant substances acting as beta subunit isoform-selective positive allosteric modulators of GABAA receptors.
PMID 15939801·Mol Pharmacol·2005
7-preclinical
Influence of the point mutation alpha-1-H101R on the assembly of gamma-aminobutyric acid type A receptors.
PMID 16272886·Neuroreport·2005
7-preclinical
Consequence of the presence of two different beta subunit isoforms in a GABA(A) receptor.
PMID 16300645·J Neurochem·2005
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 13123 E 16TH AVE
AURORA, CO 80045 - Phone
- (720) 777-1234
Quick Facts
- NPI
- 1235214966
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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