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JASON ATACK, DMD
DMD
Dentist
NPI: 1235382557Individual
Specialties, Licenses & Credentials
General Practice Dentistry
Dentist — General Practice
Code: 1223G0001X
9201(OR)
DentistPrimary
Dentist
Code: 122300000X
D9201(OR)
Research & Publications (20)
The plasma-occupancy relationship of the novel GABAA receptor benzodiazepine site ligand, alpha5IA, is similar in rats and primates.
PMID 19422390·Br J Pharmacol·2009
7-preclinical
Oxidative stress in Campylobacter jejuni: responses, resistance and regulation.
PMID 19659424·Future Microbiol·2009
6-review
Characterization of [35S]t-butylbicyclophosphorothionate ([35S]TBPS) binding to GABAA receptors in postmortem human brain.
PMID 17339834·Br J Pharmacol·2007
4-observational
Comparison of lorazepam [7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one] occupancy of rat brain gamma-aminobutyric acid(A) receptors measured using in vivo [3H]flumazenil (8-fluoro 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester) binding and [11C]flumazenil micro-positron emission tomography.
PMID 17164474·J Pharmacol Exp Ther·2007
4-observational
Rat pharmacokinetics and pharmacodynamics of a sustained release formulation of the GABAA alpha5-selective compound L-655,708.
PMID 16455808·Drug Metab Dispos·2006
7-preclinical
The in vivo properties of pagoclone in rat are most likely mediated by 5'-hydroxy pagoclone.
PMID 16430927·Neuropharmacology·2006
4-observational
L-655,708 enhances cognition in rats but is not proconvulsant at a dose selective for alpha5-containing GABAA receptors.
PMID 17046030·Neuropharmacology·2006
7-preclinical
TPA023 [7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine], an agonist selective for alpha2- and alpha3-containing GABAA receptors, is a nonsedating anxiolytic in rodents and primates.
PMID 16183706·J Pharmacol Exp Ther·2006
7-preclinical
The proconvulsant effects of the GABAA alpha5 subtype-selective compound RY-080 may not be alpha5-mediated.
PMID 16962577·Eur J Pharmacol·2006
7-preclinical
In vivo labelling of alpha5 subunit-containing GABA(A) receptors using the selective radioligand [(3)H]L-655,708.
PMID 15996568·Neuropharmacology·2005
4-observational
Anxiogenic properties of an inverse agonist selective for alpha3 subunit-containing GABA A receptors.
PMID 15655523·Br J Pharmacol·2005
7-preclinical
The benzodiazepine binding site of GABA(A) receptors as a target for the development of novel anxiolytics.
PMID 15926867·Expert Opin Investig Drugs·2005
6-review
Anxioselective compounds acting at the GABA(A) receptor benzodiazepine binding site.
PMID 12871032·Curr Drug Targets CNS Neurol Disord·2003
6-review
Kindling induced by pentylenetetrazole in rats is not directly associated with changes in the expression of NMDA or benzodiazepine receptors.
PMID 10764932·Pharmacol Biochem Behav·2000
4-observational
The complexity of the GABAA receptor shapes unique pharmacological profiles.
PMID 19576998·Drug Discov Today·2009
6-review
GABA(A) receptor subtype-selective efficacy: TPA023, an alpha2/alpha3 selective non-sedating anxiolytic and alpha5IA, an alpha5 selective cognition enhancer.
PMID 18482097·CNS Neurosci Ther·2008
6-review
The Campylobacter jejuni thiol peroxidases Tpx and Bcp both contribute to aerotolerance and peroxide-mediated stress resistance but have distinct substrate specificities.
PMID 18515414·J Bacteriol·2008
8-other
Identification of the domains in RXFP4 (GPCR142) responsible for the high affinity binding and agonistic activity of INSL5 at RXFP4 compared to RXFP3 (GPCR135).
PMID 18582868·Eur J Pharmacol·2008
4-observational
Contribution of the stereospecific methionine sulphoxide reductases MsrA and MsrB to oxidative and nitrosative stress resistance in the food-borne pathogen Campylobacter jejuni.
PMID 18667555·Microbiology (Reading)·2008
8-other
Alpha2-containing GABA(A) receptors are involved in mediating stimulant effects of cocaine.
PMID 18358520·Pharmacol Biochem Behav·2008
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 14125 SW FARMINGTON RD
BEAVERTON, OR 97005 - Phone
- (503) 646-4432
Quick Facts
- NPI
- 1235382557
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 2
- Locations
- 1
- Publications
- 20
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