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WILLIAM ATKINS, MD

MD

Obstetrics & Gynecology Physician

NPI: 1255312757Individual

Specialties, Licenses & Credentials

Obstetrics & Gynecology PhysicianPrimary

Obstetrics & Gynecology

Code: 207V00000X

MD023271E(PA)

Research & Publications (20)

Ligand binding to cytochrome P450 3A4 in phospholipid bilayer nanodiscs: the effect of model membranes.
PMID 17573349·J Biol Chem·2007
7-preclinical
Current views on the fundamental mechanisms of cytochrome P450 allosterism.
PMID 16859405·Expert Opin Drug Metab Toxicol·2006
6-review
Non-Michaelis-Menten kinetics in cytochrome P450-catalyzed reactions.
PMID 15832445·Annu Rev Pharmacol Toxicol·2005
6-review
Implications of the allosteric kinetics of cytochrome P450s.
PMID 15149623·Drug Discov Today·2004
6-review
Is there a toxicological advantage for non-hyperbolic kinetics in cytochrome P450 catalysis? Functional allostery from "distributive catalysis".
PMID 12082118·J Biol Chem·2002
8-other
Allosteric behavior in cytochrome p450-dependent in vitro drug-drug interactions: a prospective based on conformational dynamics.
PMID 11304120·Chem Res Toxicol·2001
8-other
Structural analysis of a glutathione transferase A1-1 mutant tailored for high catalytic efficiency with toxic alkenals.
PMID 19618965·Biochemistry·2009
8-other
On the use of hydrogen/deuterium exchange mass spectrometry data to improve de novo protein structure prediction.
PMID 19125403·Rapid Commun Mass Spectrom·2009
8-other
Allosteric effects on substrate dissociation from cytochrome P450 3A4 in nanodiscs observed by ensemble and single-molecule fluorescence spectroscopy.
PMID 18980315·J Am Chem Soc·2008
8-other
Principal component analysis of CYP2C9 and CYP3A4 probe substrate/inhibitor panels.
PMID 18566039·Drug Metab Dispos·2008
4-observational
Nile Red is a fluorescent allosteric substrate of cytochrome P450 3A4.
PMID 18092806·Biochemistry·2008
8-other
A quantitative index of substrate promiscuity.
PMID 18081310·Biochemistry·2008
8-other
Multiple-ligand binding in CYP2A6: probing mechanisms of cytochrome P450 cooperativity by assessing substrate dynamics.
PMID 18247580·Biochemistry·2008
8-other
Spectral resolution of a second binding site for Nile Red on cytochrome P4503A4.
PMID 18395506·Arch Biochem Biophys·2008
8-other
The stereochemical course of 4-hydroxy-2-nonenal metabolism by glutathione S-transferases.
PMID 18424441·J Biol Chem·2008
8-other
Cooperative binding of acetaminophen and caffeine within the P450 3A4 active site.
PMID 17894464·Chem Res Toxicol·2007
8-other
Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins.
PMID 17263563·Biochemistry·2007
7-preclinical
Energetics of heterotropic cooperativity between alpha-naphthoflavone and testosterone binding to CYP3A4.
PMID 17459328·Arch Biochem Biophys·2007
8-other
Functional promiscuity correlates with conformational heterogeneity in A-class glutathione S-transferases.
PMID 17561509·J Biol Chem·2007
8-other
Surface plasmon resonance analysis of antifungal azoles binding to CYP3A4 with kinetic resolution of multiple binding orientations.
PMID 16700545·Biochemistry·2006
8-other

Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.

Contact & Hours

Address
915 OLD FERN HILL RD, BLDG D, SUITE 600
WEST CHESTER, PA 19380

Location

Practice Location

915 OLD FERN HILL RD, WEST CHESTER, PA
(610) 692-3434

Quick Facts

NPI
1255312757
Entity Type
Individual
Gender
Male
Medicare
Not confirmed
Specialties
1
Locations
1
Publications
20

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