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MICHAEL KASTAN, MD
MD
Radiation Oncology Physician
NPI: 1255334371Individual
Specialties, Licenses & Credentials
Pediatric Hematology & Oncology Physician
Pediatrics — Pediatric Hematology-Oncology
Code: 2080P0207X
30557(TN)2011-01872(NC)
Radiation Oncology PhysicianPrimary
Radiology — Radiation Oncology
Code: 2085R0001X
2011-01872(NC)
Research & Publications (20)
DNA damage responses: mechanisms and roles in human disease: 2007 G.H.A. Clowes Memorial Award Lecture.
PMID 18403632·Mol Cancer Res·2008
8-other
ATM--a key determinant of multiple cellular responses to irradiation.
PMID 11765061·Acta Oncol·2001
6-review
Multiple signaling pathways involving ATM.
PMID 12760069·Cold Spring Harb Symp Quant Biol·2000
6-review
Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26.
PMID 18951086·Mol Cell·2008
7-preclinical
Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis.
PMID 18097482·J Clin Invest·2008
7-preclinical
A novel ATM-dependent pathway regulates protein phosphatase 1 in response to DNA damage.
PMID 18250156·Mol Cell Biol·2008
7-preclinical
Human T-cell leukemia virus type 1 tax attenuates the ATM-mediated cellular DNA damage response.
PMID 18434398·J Virol·2008
8-other
Assessment of protein dynamics and DNA repair following generation of DNA double-strand breaks at defined genomic sites.
PMID 18451799·Nat Protoc·2008
8-other
Transient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to ionizing radiation.
PMID 18794134·Cancer Res·2008
7-preclinical
Atm deficiency affects both apoptosis and proliferation to augment Myc-induced lymphomagenesis.
PMID 17634425·Mol Cancer Res·2007
7-preclinical
Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair.
PMID 17486112·Nat Cell Biol·2007
8-other
Ataxia telangiectasia-mutated and p53 are potential mediators of chloroquine-induced resistance to mammary carcinogenesis.
PMID 18089834·Cancer Res·2007
7-preclinical
A subtle t(3;8) results in plausible juxtaposition of MYC and BCL6 in a child with Burkitt lymphoma/leukemia and ataxia-telangiectasia.
PMID 16772123·Cancer Genet Cytogenet·2006
5-case
ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome.
PMID 17084711·Cell Metab·2006
7-preclinical
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks.
PMID 16618811·J Cell Biol·2006
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 2100 ERWIN RD
DURHAM, NC 27705 - Phone
- (919) 684-8111
Quick Facts
- NPI
- 1255334371
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 3
- Locations
- 1
- Publications
- 20
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