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PABLO MARRERO, MD

MD

Orthopaedic Surgery Physician

NPI: 1255397097Individual

Specialties, Licenses & Credentials

Orthopaedic Surgery PhysicianPrimary

Orthopaedic Surgery

Code: 207X00000X

9861(PR)

Research & Publications (18)

A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme.
PMID 19049515·FEBS J·2009
7-preclinical
Fatty acid metabolism in breast cancer cells: differential inhibitory effects of epigallocatechin gallate (EGCG) and C75.
PMID 17902053·Breast Cancer Res Treat·2008
8-other
Ketogenic HMGCS2 Is a c-Myc target gene expressed in differentiated cells of human colonic epithelium and down-regulated in colon cancer.
PMID 16940161·Mol Cancer Res·2006
8-other
An intronic peroxisome proliferator-activated receptor-binding sequence mediates fatty acid induction of the human carnitine palmitoyltransferase 1A.
PMID 16271724·J Mol Biol·2005
8-other
C75 activates malonyl-CoA sensitive and insensitive components of the CPT system.
PMID 15541339·Biochem Biophys Res Commun·2004
4-observational
Pig muscle carnitine palmitoyltransferase I (CPTI beta), with low Km for carnitine and low sensitivity to malonyl-CoA inhibition, has kinetic characteristics similar to those of the rat liver (CPTI alpha) enzyme.
PMID 15449958·Biochemistry·2004
4-observational
Functional interaction between peroxisome proliferator-activated receptors-alpha and Mef-2C on human carnitine palmitoyltransferase 1beta (CPT1beta) gene activation.
PMID 15356291·Nucleic Acids Res·2004
7-preclinical
A single amino acid change (substitution of the conserved Glu-590 with alanine) in the C-terminal domain of rat liver carnitine palmitoyltransferase I increases its malonyl-CoA sensitivity close to that observed with the muscle isoform of the enzyme.
PMID 12826662·J Biol Chem·2003
7-preclinical
Histone deacetylase inhibitors stimulate mitochondrial HMG-CoA synthase gene expression via a promoter proximal Sp1 site.
PMID 12626711·Nucleic Acids Res·2003
7-preclinical
Control of human carnitine palmitoyltransferase II gene transcription by peroxisome proliferator-activated receptor through a partially conserved peroxisome proliferator-responsive element.
PMID 12408750·Biochem J·2003
8-other
Down-regulation of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by insulin: the role of the forkhead transcription factor FKHRL1.
PMID 12027802·Biochem J·2002
7-preclinical
Embryonal rhabdomyosarcoma associated with tuberous sclerosis.
PMID 11920808·Med Pediatr Oncol·2002
5-case
Pig liver carnitine palmitoyltransferase. Chimera studies show that both the N- and C-terminal regions of the enzyme are important for the unusual high malonyl-CoA sensitivity.
PMID 11790778·J Biol Chem·2002
7-preclinical
Low activity of mitochondrial HMG-CoA synthase in liver of starved piglets is due to low levels of protein despite high mRNA levels.
PMID 11368018·Arch Biochem Biophys·2001
7-preclinical
Pig liver carnitine palmitoyltransferase I, with low Km for carnitine and high sensitivity to malonyl-CoA inhibition, is a natural chimera of rat liver and muscle enzymes.
PMID 11329295·Biochemistry·2001
4-observational
3-Hydroxy-3-methylglutaryl coenzyme A synthase-1 of Blattella germanica has structural and functional features of an active retrogene.
PMID 11222952·Insect Biochem Mol Biol·2001
4-observational
Regulation of the rat liver carnitine palmitoyltransferase I gene transcription by thyroid hormone.
PMID 11112421·Biochem Biophys Res Commun·2000
7-preclinical
Contribution of steroidogenic factor 1 to the regulation of cholesterol synthesis.
PMID 10970793·Biochem J·2000
7-preclinical

Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.

Contact & Hours

Address
AVE PONCE DE LEON #1507, SUITE 1-C PDA 22
SAN JUAN, PR 00910

Location

Practice Location

AVE PONCE DE LEON #1507, SAN JUAN, PR
(787) 725-3555

Quick Facts

NPI
1255397097
Entity Type
Individual
Gender
Male
Medicare
Not confirmed
Specialties
1
Locations
1
Publications
18

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