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RAMACHANDRA HOSMANE, M.D
M.D
Urology Physician
NPI: 1255481362Individual
Specialties, Licenses & Credentials
Urology PhysicianPrimary
Urology
Code: 208800000X
C10001653(DE)
Research & Publications (20)
Ring-expanded ("Fat") nucleosides as broad-spectrum anticancer and antiviral agents.
PMID 12173969·Curr Top Med Chem·2002
6-review
The first synthesis of a novel 5:7:5-fused diimidazodiazepine ring system and some of its chemical properties.
PMID 18816128·Org Lett·2008
8-other
Ring expanded nucleoside analogues inhibit RNA helicase and intracellular human immunodeficiency virus type 1 replication.
PMID 18680273·J Med Chem·2008
7-preclinical
Inhibition of adenosine deaminase by analogues of adenosine and inosine, incorporating a common heterocyclic base, 4(7)-amino-6(5)H-imidazo[4,5-d]pyridazin-7(4)one.
PMID 18173230·J Med Chem·2008
8-other
Chemical and biological effects of substitution of the 2-position of ring-expanded ('fat') nucleosides containing the imidazo[4,5-e][1,3]diazepine-4,8-dione ring system: the role of electronic and steric factors on glycosidic bond stability and anti-HCV activity.
PMID 17507230·Bioorg Med Chem·2007
8-other
Structure-activity relationship studies on anti-HCV activity of ring-expanded ('fat') nucleobase analogues containing the imidazo[4,5-e][1,3]diazepine-4,8-dione ring system.
PMID 17300935·Bioorg Med Chem Lett·2007
8-other
An analogue of AICAR with dual inhibitory activity against WNV and HCV NTPase/helicase: synthesis and in vitro screening of 4-carbamoyl-5-(4,6-diamino-2,5-dihydro-1,3,5-triazin-2-yl)imidazole-1-beta-D-ribofuranoside.
PMID 17289387·Bioorg Med Chem Lett·2007
8-other
Design of inhibitors against guanase: synthesis and biochemical evaluation of analogues of azepinomycin.
PMID 16920357·Bioorg Med Chem Lett·2006
7-preclinical
Nucleosides with self-complementary hydrogen-bonding motifs: synthesis and base-pairing studies of two nucleosides containing the imidazo[4,5-d]pyridazine ring system.
PMID 16765050·Bioorg Med Chem·2006
8-other
A novel imidazole nucleoside containing a diaminodihydro-S-triazine as a substituent: inhibitory activity against the West Nile virus NTPase/helicase.
PMID 16438047·Nucleosides Nucleotides Nucleic Acids·2005
8-other
Synthesis and in vitro anti-hepatitis B and C virus activities of ring-expanded ('fat') nucleobase analogues containing the imidazo[4,5-e][1,3]diazepine-4,8-dione ring system.
PMID 16213713·Bioorg Med Chem Lett·2005
8-other
A novel site-directed affinity reagent for cross-linking human hemoglobin: bis[2-(4-phosphonooxyphenoxy)carbonylethyl]phosphinic acid.
PMID 15537342·J Med Chem·2004
8-other
Application of real-time PCR for testing antiviral compounds against Lassa virus, SARS coronavirus and Ebola virus in vitro.
PMID 15451189·Antiviral Res·2004
8-other
Inhibitors of adenosine deaminase: continued studies of structure-activity relationships in analogues of coformycin.
PMID 15043152·Nucleosides Nucleotides Nucleic Acids·2004
7-preclinical
Inhibition of adenosine deaminase by novel 5:7 fused heterocycles containing the imidazo[4,5-e][1,2,4]triazepine ring system: a structure-activity relationship study.
PMID 14761206·J Med Chem·2004
7-preclinical
Potent inhibition of NTPase/helicase of the West Nile Virus by ring-expanded ("fat") nucleoside analogues.
PMID 14561097·J Med Chem·2003
8-other
Ring-expanded ("fat") nucleoside and nucleotide analogues exhibit potent in vitro activity against flaviviridae NTPases/helicases, including those of the West Nile virus, hepatitis C virus, and Japanese encephalitis virus.
PMID 12954067·J Med Chem·2003
4-observational
NTPase/helicase of Flaviviridae: inhibitors and inhibition of the enzyme.
PMID 12422230·Acta Biochim Pol·2002
6-review
in vitro inhibition of the measles virus by novel ring-expanded ('fat') nucleoside analogues containing the imidazo[4,5-e]diazepine ring system.
PMID 12419368·Bioorg Med Chem Lett·2002
7-preclinical
Characterization of imidazo[4,5-d]pyridazine nucleosides as modulators of unwinding reaction mediated by West Nile virus nucleoside triphosphatase/helicase: evidence for activity on the level of substrate and/or enzyme.
PMID 11959550·Antimicrob Agents Chemother·2002
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1408 SAVANNAH RD.
LEWZS, DE 19958 - Phone
- (302) 645-2274
Quick Facts
- NPI
- 1255481362
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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