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DOUGLAS END, MD
MD
Anesthesiology Physician
NPI: 1265643050IndividualAccepts Medicare
Education
UNIVERSITY OF TEXAS MEDICAL SCHOOL AT SAN ANTONIO
Class of 2004
Research & Publications (19)
Pharmacodynamics and pharmacokinetics of the novel thrombopoietin mimetic peptide RWJ-800088 in humans.
PMID 19238653·Clin Pharmacol Ther·2008
8-other
Impact on farnesyltransferase inhibition of 4-chlorophenyl moiety replacement in the Zarnestra series.
PMID 17316920·Eur J Med Chem·2007
8-other
Effects of the farnesyl transferase inhibitor R115777 (Zarnestra) on mammary carcinogenesis: prevention, therapy, and role of HaRas mutations.
PMID 16648579·Mol Cancer Ther·2006
7-preclinical
Phase I trial and pharmacokinetic study of the farnesyltransferase inhibitor tipifarnib in children with refractory solid tumors or neurofibromatosis type I and plexiform neurofibromas.
PMID 16421428·J Clin Oncol·2006
3-trial
Efficacy of the farnesyltransferase inhibitor R115777 in a rat mammary tumor model: role of Ha-ras mutations and use of microarray analysis in identifying potential targets.
PMID 16403772·Carcinogenesis·2006
7-preclinical
Novel triazole based inhibitors of Ras farnesyl transferase.
PMID 16216509·Bioorg Med Chem Lett·2005
8-other
Novel beta-(imidazol-4-yl)-beta-amino acids: solid-phase synthesis and study of their inhibitory activity against geranylgeranyl protein transferase type I.
PMID 15745827·Bioorg Med Chem Lett·2005
8-other
The farnesyltransferase inhibitor R115777 reduces hypoxia and matrix metalloproteinase 2 expression in human glioma xenograft.
PMID 14676133·Clin Cancer Res·2003
7-preclinical
Substituted azoloquinolines and -quinazolines as new potent farnesyl protein transferase inhibitors.
PMID 14643327·Bioorg Med Chem Lett·2003
7-preclinical
4-methyl-1,2,4-triazol-3-yl heterocycle as an alternative to the 1-methylimidazol-5-yl moiety in the farnesyltransferase inhibitor ZARNESTRA.
PMID 14643326·Bioorg Med Chem Lett·2003
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 12222 MERIT DR STE 600
DALLAS, TX 75251 - Phone
- (972) 715-5000
Quick Facts
- NPI
- 1265643050
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 2
- Years in Practice
- 22
- Publications
- 19
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