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KATHLEEN RYMAN, MD
MD
Cardiovascular Disease Physician
NPI: 1275604191Individual
Specialties, Licenses & Credentials
Cardiovascular Disease PhysicianPrimary
Internal Medicine — Cardiovascular Disease
Code: 207RC0000X
G66600(CA)
Research & Publications (20)
Effects of PKR/RNase L-dependent and alternative antiviral pathways on alphavirus replication and pathogenesis.
PMID 11952147·Viral Immunol·2002
7-preclinical
Alpha/beta interferon protects adult mice from fatal Sindbis virus infection and is an important determinant of cell and tissue tropism.
PMID 10708454·J Virol·2000
7-preclinical
Similarities and differences in antagonism of neuron alpha/beta interferon responses by Venezuelan equine encephalitis and Sindbis alphaviruses.
PMID 19641001·J Virol·2009
7-preclinical
Type I interferon induction is correlated with attenuation of a South American eastern equine encephalitis virus strain in mice.
PMID 19539968·Virology·2009
7-preclinical
Eastern and Venezuelan equine encephalitis viruses differ in their ability to infect dendritic cells and macrophages: impact of altered cell tropism on pathogenesis.
PMID 18768986·J Virol·2008
4-observational
Alpha/beta interferon inhibits cap-dependent translation of viral but not cellular mRNA by a PKR-independent mechanism.
PMID 18160435·J Virol·2008
7-preclinical
Identification and characterization of interferon-induced proteins that inhibit alphavirus replication.
PMID 17686841·J Virol·2007
7-preclinical
Non-pathogenic Sindbis virus causes hemorrhagic fever in the absence of alpha/beta and gamma interferons.
PMID 17681583·Virology·2007
7-preclinical
The C-terminal domain of RNA Pol II helps ensure that editing precedes splicing of the GluR-B transcript.
PMID 17525170·RNA·2007
8-other
Early restriction of alphavirus replication and dissemination contributes to age-dependent attenuation of systemic hyperinflammatory disease.
PMID 17251570·J Gen Virol·2007
7-preclinical
Heparan sulfate binding can contribute to the neurovirulence of neuroadapted and nonneuroadapted Sindbis viruses.
PMID 17215278·J Virol·2007
7-preclinical
Targeting Sindbis virus-based vectors to Fc receptor-positive cell types.
PMID 15922395·Virology·2005
7-preclinical
Sindbis virus translation is inhibited by a PKR/RNase L-independent effector induced by alpha/beta interferon priming of dendritic cells.
PMID 15650175·J Virol·2005
7-preclinical
Genetic relationships and evolution of genotypes of yellow fever virus and other members of the yellow fever virus group within the Flavivirus genus based on the 3' noncoding region.
PMID 15331698·J Virol·2004
4-observational
Conformational changes in Sindbis virions resulting from exposure to low pH and interactions with cells suggest that cell penetration may occur at the cell surface in the absence of membrane fusion.
PMID 15207623·Virology·2004
7-preclinical
Attenuation of Sindbis virus variants incorporating uncleaved PE2 glycoprotein is correlated with attachment to cell-surface heparan sulfate.
PMID 15063111·Virology·2004
7-preclinical
DC-SIGN and L-SIGN can act as attachment receptors for alphaviruses and distinguish between mosquito cell- and mammalian cell-derived viruses.
PMID 14581539·J Virol·2003
7-preclinical
Sindbis virus vectors designed to express a foreign protein as a cleavable component of the viral structural polyprotein.
PMID 12719552·J Virol·2003
7-preclinical
PE2 cleavage mutants of Sindbis virus: correlation between viral infectivity and pH-dependent membrane fusion activation of the spike heterodimer.
PMID 11602759·J Virol·2001
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 5601 DE SOTO AVE
WOODLAND HILLS, CA 91367 - Phone
- (818) 719-2000
Quick Facts
- NPI
- 1275604191
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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