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THOMAS WICKHAM, DO, MPH
DO, MPH
Family Medicine Physician
NPI: 1295363091IndividualAccepts Medicare
Specialties, Licenses & Credentials
Family Medicine PhysicianPrimary
Family Medicine
Code: 207Q00000X
1014436(MA)
CMS Specialties
PrimaryFAMILY PRACTICE
Education
NEW YORK COLLEGE OF OSTEO MEDICINE OF NEW YORK INSTITUTE OF TECHNOLOGY
Class of 2020
Research & Publications (20)
A novel approach and a novel mechanism for stealthing gene delivery vehicles.
PMID 10947936·Mol Ther·2000
7-preclinical
Experimental treatment of ovarian cancers by adenovirus vectors combining receptor targeting and selective expression of tumor necrosis factor.
PMID 17786312·Int J Oncol·2007
7-preclinical
Epitopes expressed in different adenovirus capsid proteins induce different levels of epitope-specific immunity.
PMID 16699033·J Virol·2006
7-preclinical
Induction of leukemia-specific CD8+ cytotoxic T cells with autologous myeloid leukemic cells maturated with a fiber-modified adenovirus encoding TNF-alpha.
PMID 15922966·Mol Ther·2005
8-other
Protection against P. aeruginosa with an adenovirus vector containing an OprF epitope in the capsid.
PMID 15841217·J Clin Invest·2005
7-preclinical
Histone deacetylase inhibitors upregulate expression of the coxsackie adenovirus receptor (CAR) preferentially in bladder cancer cells.
PMID 15118762·Cancer Gene Ther·2004
8-other
Modification to the capsid of the adenovirus vector that enhances dendritic cell infection and transgene-specific cellular immune responses.
PMID 14963160·J Virol·2004
7-preclinical
Ablating CAR and integrin binding in adenovirus vectors reduces nontarget organ transduction and permits sustained bloodstream persistence following intraperitoneal administration.
PMID 14759806·Mol Ther·2004
7-preclinical
Binding of adenoviral fiber knob to the coxsackievirus-adenovirus receptor is crucial for transduction of fetal muscle.
PMID 12804146·Hum Gene Ther·2003
7-preclinical
The role of capsid-endothelial interactions in the innate immune response to adenovirus vectors.
PMID 12804145·Hum Gene Ther·2003
7-preclinical
Gamma-irradiation enhances transgene expression in leukemic cells.
PMID 12571630·Gene Ther·2003
7-preclinical
Selective gene transfer into primary human gastric tumors using epithelial cell adhesion molecule-targeted adenoviral vectors with ablated native tropism.
PMID 12396621·Hum Gene Ther·2002
8-other
Modifications in adenoviral coat fiber proteins and transcriptional regulatory sequences enhance transgene expression.
PMID 12180715·J Rheumatol·2002
7-preclinical
Adenovirus binding to the coxsackievirus and adenovirus receptor or integrins is not required to elicit brain inflammation but is necessary to transduce specific neural cell types.
PMID 11884569·J Virol·2002
7-preclinical
Efficient and selective gene transfer into primary human brain tumors by using single-chain antibody-targeted adenoviral vectors with native tropism abolished.
PMID 11861842·J Virol·2002
7-preclinical
Head injuries in infants: the risks of bouncy chairs and car seats.
PMID 11861231·Arch Dis Child·2002
8-other
Activation of p38 and ERK signaling during adenovirus vector cell entry lead to expression of the C-X-C chemokine IP-10.
PMID 11799150·J Virol·2002
7-preclinical
Reducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactions.
PMID 11689608·J Virol·2001
7-preclinical
Transduction and apoptosis induction in the rat prostate, using adenovirus vectors.
PMID 11506693·Hum Gene Ther·2001
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 155 FRANKLIN RD
FITCHBURG, MA 01420 - Phone
- (978) 345-1919
Quick Facts
- NPI
- 1295363091
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 1
- Years in Practice
- 6
- Publications
- 20
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