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DAVID SHUSTER, DO
DO
Orthopaedic Surgery Physician
NPI: 1295474955Individual
Specialties, Licenses & Credentials
Orthopaedic Surgery PhysicianPrimary
Orthopaedic Surgery
Code: 207X00000X
5151015582(MI)
Research & Publications (20)
A phase I study of eribulin mesylate (E7389), a mechanistically novel inhibitor of microtubule dynamics, in patients with advanced solid malignancies.
PMID 19509177·Clin Cancer Res·2009
3-trial
Phase I study of eribulin mesylate administered once every 21 days in patients with advanced solid tumors.
PMID 19509146·Clin Cancer Res·2009
3-trial
Phase II study of eribulin mesylate, a halichondrin B analog, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane.
PMID 19349550·J Clin Oncol·2009
3-trial
Synthesis and SAR of new pyrrolo[2,1-f][1,2,4]triazines as potent p38 alpha MAP kinase inhibitors.
PMID 18364256·Bioorg Med Chem Lett·2008
7-preclinical
The discovery of (R)-2-(sec-butylamino)-N-(2-methyl-5-(methylcarbamoyl)phenyl) thiazole-5-carboxamide (BMS-640994)-A potent and efficacious p38alpha MAP kinase inhibitor.
PMID 18313298·Bioorg Med Chem Lett·2008
7-preclinical
Gene-environment interactions in a mutant mouse kindred with native airway constrictor hyperresponsiveness.
PMID 18167028·Mamm Genome·2008
7-preclinical
Design, synthesis, and anti-inflammatory properties of orally active 4-(phenylamino)-pyrrolo[2,1-f][1,2,4]triazine p38alpha mitogen-activated protein kinase inhibitors.
PMID 18072718·J Med Chem·2008
7-preclinical
Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419).
PMID 17585753·J Med Chem·2007
7-preclinical
2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (dasatinib, BMS-354825) as a potent pan-Src kinase inhibitor.
PMID 17154512·J Med Chem·2006
7-preclinical
Inflammatory myofibroblastic tumors of the urinary tract: a clinicopathologic study of 46 cases, including a malignant example inflammatory fibrosarcoma and a subset associated with high-grade urothelial carcinoma.
PMID 17122505·Am J Surg Pathol·2006
8-other
Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors.
PMID 16682193·Bioorg Med Chem Lett·2006
7-preclinical
Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors.
PMID 16481166·Bioorg Med Chem Lett·2006
7-preclinical
A canine model of cutaneous late-phase reactions: prednisolone inhibition of cellular and cytokine responses.
PMID 16423053·Immunology·2006
7-preclinical
Rapid glacial erosion at 1.8 Ma revealed by 4He/3He thermochronometry.
PMID 16339442·Science·2005
8-other
5-Cyanopyrimidine derivatives as a novel class of potent, selective, and orally active inhibitors of p38alpha MAP kinase.
PMID 16190753·J Med Chem·2005
7-preclinical
Martian surface paleotemperatures from thermochronology of meteorites.
PMID 16040703·Science·2005
8-other
The discovery of orally active triaminotriazine aniline amides as inhibitors of p38 MAP kinase.
PMID 15566298·J Med Chem·2004
7-preclinical
Discovery of novel 2-(aminoheteroaryl)-thiazole-5-carboxamides as potent and orally active Src-family kinase p56(Lck) inhibitors.
PMID 15546730·Bioorg Med Chem Lett·2004
7-preclinical
A European survey of antimicrobial susceptibility among zoonotic and commensal bacteria isolated from food-producing animals.
PMID 15375107·J Antimicrob Chemother·2004
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 28050 GRAND RIVER AVE
FARMINGTON HILLS, MI 48336 - Phone
- (248) 372-9600
Quick Facts
- NPI
- 1295474955
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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