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MICHAEL MACAULEY, M.D.
M.D.
Hospice and Palliative Medicine (Internal Medicine) Physician
NPI: 1295969061IndividualAccepts Medicare
Specialties, Licenses & Credentials
Internal Medicine Physician
Internal Medicine
Code: 207R00000X
MD445241(PA)MT194419(PA)
Hospice and Palliative Medicine (Internal Medicine) PhysicianPrimary
Internal Medicine — Hospice and Palliative Medicine
Code: 207RH0002X
MD445241(PA)
Education
PENNSYLVANIA STATE UNIVERSITY COLLEGE OF MEDICINE
Class of 2009
Research & Publications (20)
Increasing O-GlcNAc levels: An overview of small-molecule inhibitors of O-GlcNAcase.
PMID 19664691·Biochim Biophys Acta·2010
6-review
Enzymatic characterization and inhibition of the nuclear variant of human O-GlcNAcase.
PMID 19423084·Carbohydr Res·2009
8-other
Elevation of global O-GlcNAc levels in 3T3-L1 adipocytes by selective inhibition of O-GlcNAcase does not induce insulin resistance.
PMID 18842583·J Biol Chem·2008
7-preclinical
Beads-on-a-string, characterization of ETS-1 sumoylated within its flexible N-terminal sequence.
PMID 16319071·J Biol Chem·2006
7-preclinical
O-GlcNAcase catalyzes cleavage of thioglycosides without general acid catalysis.
PMID 16332065·J Am Chem Soc·2005
8-other
O-GlcNAcase uses substrate-assisted catalysis: kinetic analysis and development of highly selective mechanism-inspired inhibitors.
PMID 15795231·J Biol Chem·2005
7-preclinical
Structural and dynamic independence of isopeptide-linked RanGAP1 and SUMO-1.
PMID 15355965·J Biol Chem·2004
8-other
A selective inhibitor Gal-PUGNAc of human lysosomal beta-hexosaminidases modulates levels of the ganglioside GM2 in neuroblastoma cells.
PMID 19130519·Angew Chem Int Ed Engl·2009
8-other
Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc).
PMID 19666537·Proc Natl Acad Sci U S A·2009
7-preclinical
Unconventional ligand activation of herpesvirus entry mediator signals cell survival.
PMID 19332782·Proc Natl Acad Sci U S A·2009
7-preclinical
Streptococcus pneumoniae endohexosaminidase D, structural and mechanistic insight into substrate-assisted catalysis in family 85 glycoside hydrolases.
PMID 19181667·J Biol Chem·2009
8-other
A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo.
PMID 18587388·Nat Chem Biol·2008
7-preclinical
Structure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylation.
PMID 18536723·Nat Struct Mol Biol·2008
8-other
Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise.
PMID 17227027·J Am Chem Soc·2007
8-other
Functional analysis of a group A streptococcal glycoside hydrolase Spy1600 from family 84 reveals it is a beta-N-acetylglucosaminidase and not a hyaluronidase.
PMID 16822234·Biochem J·2006
7-preclinical
Structure and mechanism of a bacterial beta-glucosaminidase having O-GlcNAcase activity.
PMID 16565725·Nat Struct Mol Biol·2006
4-observational
Identification of Asp174 and Asp175 as the key catalytic residues of human O-GlcNAcase by functional analysis of site-directed mutants.
PMID 16533067·Biochemistry·2006
4-observational
A highly concise preparation of O-deacetylated arylthioglycosides of N-acetyl-D-glucosamine from 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-alpha-D-glucopyranosyl chloride and aryl thiols or disulfides.
PMID 16472788·Carbohydr Res·2006
8-other
Dealing with electronic waste: modeling the costs and environmental benefits of computer monitor disposal.
PMID 12767859·J Environ Manage·2003
8-other
PC-based visual stimuli for behavioural and electrophysiological studies of optic flow field detection.
PMID 11850039·J Neurosci Methods·2002
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 500 UNIVERSITY DR
HERSHEY, PA 17033 - Phone
- (800) 243-1455
Quick Facts
- NPI
- 1295969061
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 3
- Locations
- 1
- Years in Practice
- 17
- Publications
- 20
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