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JAMES GRATTON, M.D.
M.D.
Emergency Medicine Physician
NPI: 1306279864IndividualAccepts Medicare
Specialties, Licenses & Credentials
Emergency Medicine PhysicianPrimary
Emergency Medicine
Code: 207P00000X
29593-R(PR)
CMS Specialties
PrimaryEMERGENCY MEDICINE
Education
OTHER
Class of 2012
Research & Publications (20)
Cell-permeable peptides improve cellular uptake and therapeutic gene delivery of replication-deficient viruses in cells and in vivo.
PMID 12598894·Nat Med·2003
7-preclinical
Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells.
PMID 11387313·J Biol Chem·2001
7-preclinical
Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1.
PMID 10781589·J Biol Chem·2000
7-preclinical
Phosphorylation of endothelial nitric oxide synthase by atypical PKC zeta contributes to angiopoietin-1-dependent inhibition of VEGF-induced endothelial permeability in vitro.
PMID 19564638·Blood·2009
7-preclinical
Sphingosine-1-phosphate: a novel nonhypoxic activator of hypoxia-inducible factor-1 in vascular cells.
PMID 19423865·Arterioscler Thromb Vasc Biol·2009
7-preclinical
New role for the protein tyrosine phosphatase DEP-1 in Akt activation and endothelial cell survival.
PMID 18936167·Mol Cell Biol·2009
8-other
Src-mediated phosphorylation of Hsp90 in response to vascular endothelial growth factor (VEGF) is required for VEGF receptor-2 signaling to endothelial NO synthase.
PMID 17855507·Mol Biol Cell·2007
7-preclinical
Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function.
PMID 17702744·J Biol Chem·2007
7-preclinical
Phosphorylation of tyrosine 801 of vascular endothelial growth factor receptor-2 is necessary for Akt-dependent endothelial nitric-oxide synthase activation and nitric oxide release from endothelial cells.
PMID 17303569·J Biol Chem·2007
4-observational
Angiotensin II/AT2 receptor-induced vasodilation in stroke-prone spontaneously hypertensive rats involves nitric oxide and cGMP-dependent protein kinase.
PMID 17082724·J Hypertens·2006
7-preclinical
Nitric oxide signaling via nuclearized endothelial nitric-oxide synthase modulates expression of the immediate early genes iNOS and mPGES-1.
PMID 16574649·J Biol Chem·2006
7-preclinical
Essential requirement for sphingosine kinase activity in eNOS-dependent NO release and vasorelaxation.
PMID 16322129·FASEB J·2006
7-preclinical
Dissociation of beta-arrestin from internalized bradykinin B2 receptor is necessary for receptor recycling and resensitization.
PMID 15993749·Cell Signal·2005
7-preclinical
A role for caveolin-1 in post-injury reactive neuronal plasticity.
PMID 15686485·J Neurochem·2005
4-observational
Vanadate is a potent activator of endothelial nitric-oxide synthase: evidence for the role of the serine/threonine kinase Akt and the 90-kDa heat shock protein.
PMID 14742683·Mol Pharmacol·2004
7-preclinical
The caveolin scaffolding domain modifies 2-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor binding properties by inhibiting phospholipase A2 activity.
PMID 14561756·J Biol Chem·2004
7-preclinical
Selective inhibition of tumor microvascular permeability by cavtratin blocks tumor progression in mice.
PMID 12892711·Cancer Cell·2003
7-preclinical
Angiopoietin-1 activates both anti- and proapoptotic mitogen-activated protein kinases.
PMID 12824293·FASEB J·2003
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 917 AVE TITO CASTRO
PONCE, PR 00716 - Phone
- (787) 844-2080
Quick Facts
- NPI
- 1306279864
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 1
- Years in Practice
- 14
- Publications
- 20
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