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GEOFFREY POSNER, MD
MD
Ophthalmology Physician
NPI: 1306848296Individual
Specialties, Licenses & Credentials
Ophthalmology PhysicianPrimary
Ophthalmology
Code: 207W00000X
016661(GA)
Research & Publications (20)
Vitamin D receptor modulates the neoplastic phenotype through antagonistic growth regulatory signals.
PMID 19184984·Mol Carcinog·2009
7-preclinical
Accumulation of artemisinin trioxane derivatives within neutral lipids of Plasmodium falciparum malaria parasites is endoperoxide-dependent.
PMID 19022224·Biochem Pharmacol·2009
7-preclinical
Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells.
PMID 19186946·J Med Chem·2009
7-preclinical
Artemisinin derivatives inhibit Toxoplasma gondii in vitro at multiple steps in the lytic cycle.
PMID 18988681·J Antimicrob Chemother·2009
7-preclinical
Malaria-infected mice live until at least day 30 after a new monomeric trioxane combined with mefloquine are administered together in a single low oral dose.
PMID 19586052·J Med Chem·2009
7-preclinical
'Novel alkyl side chain sulfone 1alpha,25-dihydroxyvitamin D3 analogs: a comparison of in vitro antiproliferative activities and in vivo calcemic activities'.
PMID 19577932·Bioorg Med Chem·2009
4-observational
Malaria-infected mice are cured by oral administration of new artemisinin derivatives.
PMID 18232653·J Med Chem·2008
7-preclinical
Effect of artemisinins and other endoperoxides on nitric oxide-related signaling pathway in RAW 264.7 mouse macrophage cells.
PMID 18472018·Nitric Oxide·2008
7-preclinical
Electronically stabilized versions of the antimalarial acetal trioxanes artemether and artesunate.
PMID 18353653·Bioorg Med Chem·2008
7-preclinical
Asymmetric, organocatalytic, three-step synthesis of gamma-hydroxy-(E)-alpha,beta-unsaturated sulfones and esters.
PMID 18811178·Org Lett·2008
8-other
Difluoromethyl analogs of the natural hormone 1alpha,25-dihydroxyvitamin D3: Design, synthesis, and preliminary biological evaluation.
PMID 17218093·J Steroid Biochem Mol Biol·2007
7-preclinical
Malaria-infected mice are cured by a single dose of novel artemisinin derivatives.
PMID 17439113·J Med Chem·2007
7-preclinical
Antiproliferative, low-calcemic, fluorinated sulfone analogs of 1alpha,25-dihydroxyvitamin D3: chemical synthesis and biological evaluation.
PMID 17560112·Bioorg Med Chem·2007
7-preclinical
Cyclopentanone ring expansion leading to functionalized delta-lactams: short synthesis of simple sedum alkaloids.
PMID 17564459·Org Lett·2007
8-other
Less-calcemic vitamin D analogs enhance creatine kinase specific activity and modulate responsiveness to gonadal steroids in rat skeletal tissues.
PMID 17392597·J Endocrinol Invest·2007
4-observational
Low-calcemic, highly antiproliferative, 23-oxa ether analogs of the natural hormone 1 alpha,25-dihydroxyvitamin D3: design, synthesis, and preliminary biological evaluation.
PMID 17924616·J Med Chem·2007
7-preclinical
A 24-phenylsulfone analog of vitamin D inhibits 1alpha,25-dihydroxyvitamin D(3) degradation in vitamin D metabolism-competent cells.
PMID 17182978·J Pharmacol Exp Ther·2007
8-other
Unexpected steric effects of "remote" alkyl groups on the rate of conjugate additions to alkyl alpha,beta-ethylenic sulfones, sulfoxides, and esters.
PMID 17341116·J Org Chem·2007
8-other
Systemic treatments with the low-calcemic 1,25(OH)(2)D(3) analogs JKF or QW increase both the morphological and biochemical responses to estradiol-17beta in rat tibiae.
PMID 17163482·J Cell Biochem·2007
7-preclinical
Biological mechanisms of action of novel C-10 non-acetal trioxane dimers in prostate cancer cell lines.
PMID 17181166·J Med Chem·2006
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1230 JOHNSON FERRY PL, SUITE B-10
MARIETTA, GA 30068 - Phone
- (770) 977-8000
Quick Facts
- NPI
- 1306848296
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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