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MATTHEW FRALEY, MD

MD

Cardiovascular Disease Physician

NPI: 1326187352IndividualAccepts Medicare

Specialties, Licenses & Credentials

Cardiovascular Disease PhysicianPrimary

Internal Medicine — Cardiovascular Disease

Code: 207RC0000X

036-123183(IL)2004021586(MO)

CMS Specialties

PrimaryCARDIOVASCULAR DISEASE (CARDIOLOGY)

Education

SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE

Class of 2001

Research & Publications (20)

Obesity and the electrocardiogram.
PMID 16246213·Obes Rev·2005
6-review
Property-based design of KDR kinase inhibitors.
PMID 15032725·Curr Med Chem·2004
6-review
Positive allosteric modulators of the metabotropic glutamate receptor 2 for the treatment of schizophrenia.
PMID 19552508·Expert Opin Ther Pat·2009
6-review
Development of thioquinazolinones, allosteric Chk1 kinase inhibitors.
PMID 19155174·Bioorg Med Chem Lett·2009
8-other
Kinesin spindle protein (KSP) inhibitors. 9. Discovery of (2S)-4-(2,5-difluorophenyl)-n-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the treatment of taxane-refractory cancer.
PMID 18578472·J Med Chem·2008
8-other
Synthesis and evaluation of substituted benzoisoquinolinones as potent inhibitors of Chk1 kinase.
PMID 17900896·Bioorg Med Chem Lett·2007
8-other
Kinesin spindle protein (KSP) inhibitors. Part 7: Design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP.
PMID 17804233·Bioorg Med Chem Lett·2007
7-preclinical
Optimization of a pyrazoloquinolinone class of Chk1 kinase inhibitors.
PMID 17804227·Bioorg Med Chem Lett·2007
8-other
Kinesin spindle protein (KSP) inhibitors. Part 6: Design and synthesis of 3,5-diaryl-4,5-dihydropyrazole amides as potent inhibitors of the mitotic kinesin KSP.
PMID 17761419·Bioorg Med Chem Lett·2007
8-other
Kinesin spindle protein (KSP) inhibitors. Part V: discovery of 2-propylamino-2,4-diaryl-2,5-dihydropyrroles as potent, water-soluble KSP inhibitors, and modulation of their basicity by beta-fluorination to overcome cellular efflux by P-glycoprotein.
PMID 17395460·Bioorg Med Chem Lett·2007
8-other

Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.

Contact & Hours

Via practice · 2 locations total

Address
1225 GRAHAM RD STE C-2310
FLORISSANT, MO 63031

Locations (2)

Practice Location

1225 GRAHAM RD STE C-2310, FLORISSANT, MO
(618) 228-4215

Practice Location

6810 State Route 162 Ste 102, Maryville, IL
(618) 228-4215

Quick Facts

NPI
1326187352
Entity Type
Individual
Gender
Male
Medicare
Accepted
Specialties
2
Locations
2
Years in Practice
25
Publications
20

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