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MICHAEL DARVILLE, MD
MD
Internal Medicine Physician
NPI: 1346217999Individual
Specialties, Licenses & Credentials
Internal Medicine PhysicianPrimary
Internal Medicine
Code: 207R00000X
39795(TN)
Hospitalist Physician
Hospitalist
Code: 208M00000X
39795(TN)
Research & Publications (19)
Notch signaling: a mediator of beta-cell de-differentiation in diabetes?
PMID 16337608·Biochem Biophys Res Commun·2006
7-preclinical
BCL-6: a possible missing link for anti-inflammatory PPAR-delta signalling in pancreatic beta cells.
PMID 16896941·Diabetologia·2006
7-preclinical
Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kappaB-mediated gene expression in insulin-producing INS-1E cells.
PMID 16283237·Diabetologia·2005
7-preclinical
Macrophages enhance the radiosensitizing activity of lipid A: a novel role for immune cells in tumor cell radioresponse.
PMID 15380597·Int J Radiat Oncol Biol Phys·2004
7-preclinical
Suppressor of cytokine signalling (SOCS)-3 protects beta cells against IL-1beta-mediated toxicity through inhibition of multiple nuclear factor-kappaB-regulated proapoptotic pathways.
PMID 15578154·Diabetologia·2004
7-preclinical
An octamer motif is required for activation of the inducible nitric oxide synthase promoter in pancreatic beta-cells.
PMID 14630716·Endocrinology·2004
7-preclinical
Molecular regulation of monocyte chemoattractant protein-1 expression in pancreatic beta-cells.
PMID 12540607·Diabetes·2003
7-preclinical
Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells.
PMID 14578289·Diabetes·2003
7-preclinical
Use of microarray analysis to unveil transcription factor and gene networks contributing to Beta cell dysfunction and apoptosis.
PMID 14679040·Ann N Y Acad Sci·2003
8-other
Double-stranded RNA cooperates with interferon-gamma and IL-1 beta to induce both chemokine expression and nuclear factor-kappa B-dependent apoptosis in pancreatic beta-cells: potential mechanisms for viral-induced insulitis and beta-cell death in type 1 diabetes mellitus.
PMID 11897677·Endocrinology·2002
7-preclinical
Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis.
PMID 11574401·Diabetes·2001
7-preclinical
Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation of manganese superoxide dismutase.
PMID 11524388·Circulation·2001
7-preclinical
Cytokine induction of Fas gene expression in insulin-producing cells requires the transcription factors NF-kappaB and C/EBP.
PMID 11473033·Diabetes·2001
7-preclinical
Double-stranded ribonucleic acid (RNA) induces beta-cell Fas messenger RNA expression and increases cytokine-induced beta-cell apoptosis.
PMID 11356709·Endocrinology·2001
7-preclinical
beta-cell apoptosis and defense mechanisms: lessons from type 1 diabetes.
PMID 11272205·Diabetes·2001
7-preclinical
Outcome and clinical course of 100 patients with adenovirus infection following bone marrow transplantation.
PMID 11223974·Bone Marrow Transplant·2000
8-other
Glutathione depletion inhibits IL-1 beta-stimulated nitric oxide production by reducing inducible nitric oxide synthase gene expression.
PMID 10976000·Cytokine·2000
7-preclinical
NF-kappaB is required for cytokine-induced manganese superoxide dismutase expression in insulin-producing cells.
PMID 10614634·Endocrinology·2000
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1412 COUNTY HOSPITAL RD
NASHVILLE, TN 37218 - Phone
- (615) 364-4158
Quick Facts
- NPI
- 1346217999
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 2
- Locations
- 1
- Publications
- 19
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