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LAWRENCE MAILE, PH.D.
PH.D.
Psychologist
NPI: 1346554458Individual
Specialties, Licenses & Credentials
PsychologistPrimary
Psychologist
Code: 103T00000X
392(AK)
Research & Publications (20)
Glucose-oxidized low-density lipoproteins enhance insulin-like growth factor I-stimulated smooth muscle cell proliferation by inhibiting integrin-associated protein cleavage.
PMID 18974270·Endocrinology·2009
7-preclinical
Modulation of integrin antagonist signaling by ligand binding of the heparin-binding domain of vitronectin to the alphaVbeta3 integrin.
PMID 18615592·J Cell Biochem·2008
7-preclinical
Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells.
PMID 18420583·J Biol Chem·2008
7-preclinical
Glucose regulation of integrin-associated protein cleavage controls the response of vascular smooth muscle cells to insulin-like growth factor-I.
PMID 18292237·Mol Endocrinol·2008
7-preclinical
Integrin-associated protein association with SRC homology 2 domain containing tyrosine phosphatase substrate 1 regulates igf-I signaling in vivo.
PMID 18633106·Diabetes·2008
7-preclinical
Expression of the human beta3 integrin subunit in mouse smooth muscle cells enhances IGF-I-stimulated signaling and proliferation.
PMID 17607710·J Cell Physiol·2008
7-preclinical
Role of the integrin alphaVbeta3 in mediating increased smooth muscle cell responsiveness to IGF-I in response to hyperglycemic stress.
PMID 17412627·Growth Horm IGF Res·2007
6-review
Hyperglycemia alters the responsiveness of smooth muscle cells to insulin-like growth factor-I.
PMID 17255202·Endocrinology·2007
7-preclinical
Regulation of igf-I signaling in retinal endothelial cells by hyperglycemia.
PMID 17652764·Invest Ophthalmol Vis Sci·2007
7-preclinical
Insulin-like growth factor-I signaling in smooth muscle cells is regulated by ligand binding to the 177CYDMKTTC184 sequence of the beta3-subunit of alphaVbeta3.
PMID 16195248·Mol Endocrinol·2006
8-other
The heparin binding domain of vitronectin is the region that is required to enhance insulin-like growth factor-I signaling.
PMID 16322097·Mol Endocrinol·2006
7-preclinical
Recruitment of the tyrosine phosphatase Src homology 2 domain tyrosine phosphatase-2 to the p85 subunit of phosphatidylinositol-3 (PI-3) kinase is required for insulin-like growth factor-I-dependent PI-3 kinase activation in smooth muscle cells.
PMID 16306077·Endocrinology·2006
7-preclinical
Insulin-like growth factor binding protein-5 (IGFBP-5) interacts with thrombospondin-1 to induce negative regulatory effects on IGF-I actions.
PMID 15700281·J Cell Physiol·2005
7-preclinical
Role of SHPS-1 in the regulation of insulin-like growth factor I-stimulated Shc and mitogen-activated protein kinase activation in vascular smooth muscle cells.
PMID 15888547·Mol Biol Cell·2005
7-preclinical
DOK1 mediates SHP-2 binding to the alphaVbeta3 integrin and thereby regulates insulin-like growth factor I signaling in cultured vascular smooth muscle cells.
PMID 15546884·J Biol Chem·2005
7-preclinical
Interaction between insulin-like growth factor-I receptor and alphaVbeta3 integrin linked signaling pathways: cellular responses to changes in multiple signaling inputs.
PMID 15528274·Mol Endocrinol·2005
6-review
Integrin-associated protein binding domain of thrombospondin-1 enhances insulin-like growth factor-I receptor signaling in vascular smooth muscle cells.
PMID 14563713·Circ Res·2003
7-preclinical
The association between integrin-associated protein and SHPS-1 regulates insulin-like growth factor-I receptor signaling in vascular smooth muscle cells.
PMID 12972543·Mol Biol Cell·2003
7-preclinical
Tyrosine phosphorylation of the beta3-subunit of the alphaVbeta3 integrin is required for embrane association of the tyrosine phosphatase SHP-2 and its further recruitment to the insulin-like growth factor I receptor.
PMID 12791772·Mol Endocrinol·2003
8-other
Minireview: Integral membrane proteins that function coordinately with the insulin-like growth factor I receptor to regulate intracellular signaling.
PMID 12697669·Endocrinology·2003
6-review
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 3700 PIPER ST
ANCHORAGE, AK 99508 - Phone
- (907) 269-7168
Quick Facts
- NPI
- 1346554458
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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