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STEVEN PYKE, M.D.
M.D.
Family Medicine Physician
NPI: 1366493116IndividualAccepts Medicare
Specialties, Licenses & Credentials
Family Medicine PhysicianPrimary
Family Medicine
Code: 207Q00000X
G78611(CA)
Education
UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE
Class of 1992
Research & Publications (20)
Carbonyl-scavenging drugs & protection against carbonyl stress-associated cell injury.
PMID 18473924·Mini Rev Med Chem·2008
6-review
Sequential and selective Buchwald-Hartwig amination reactions for the controlled functionalization of 6-bromo-2-chloroquinoline: synthesis of ligands for the Tec Src homology 3 domain.
PMID 18950225·J Org Chem·2008
7-preclinical
Michael addition of acrolein to lysinyl and N-terminal residues of a model peptide: targets for cytoprotective hydrazino drugs.
PMID 17318925·Rapid Commun Mass Spectrom·2007
8-other
Antimicrobial compounds from the Australian desert plant Eremophila neglecta.
PMID 17844993·J Nat Prod·2007
8-other
Enantioselective assay for the determination of perhexiline enantiomers in human plasma by liquid chromatography.
PMID 16434242·J Chromatogr B Analyt Technol Biomed Life Sci·2006
4-observational
Hydralazine inhibits rapid acrolein-induced protein oligomerization: role of aldehyde scavenging and adduct trapping in cross-link blocking and cytoprotection.
PMID 16368895·Mol Pharmacol·2006
7-preclinical
Synthesis of N-benzylated-2-aminoquinolines as ligands for the Tec SH3 domain.
PMID 16260132·Bioorg Med Chem Lett·2006
8-other
Synthesis of 5-, 6- and 7-substituted-2-aminoquinolines as SH3 domain ligands.
PMID 15999186·Org Biomol Chem·2005
8-other
Differences in lysine adduction by acrolein and methyl vinyl ketone: implications for cytotoxicity in cultured hepatocytes.
PMID 16300370·Chem Res Toxicol·2005
7-preclinical
Reactivity of hydrazinophthalazine drugs with the lipid peroxidation products acrolein and crotonaldehyde.
PMID 15351821·Org Biomol Chem·2004
7-preclinical
Protein adduct-trapping by hydrazinophthalazine drugs: mechanisms of cytoprotection against acrolein-mediated toxicity.
PMID 14978244·Mol Pharmacol·2004
7-preclinical
Strong protein adduct trapping accompanies abolition of acrolein-mediated hepatotoxicity by hydralazine in mice.
PMID 15131244·J Pharmacol Exp Ther·2004
7-preclinical
Identification and specificity studies of small-molecule ligands for SH3 protein domains.
PMID 15481978·J Med Chem·2004
7-preclinical
Sudden, unexpected cardiac or unexplained death in England: a national survey.
PMID 12651971·QJM·2003
8-other
Reactivity with Tris(hydroxymethyl)aminomethane confounds immunodetection of acrolein-adducted proteins.
PMID 14565760·Chem Res Toxicol·2003
7-preclinical
Enhanced synergy between fluticasone propionate and salmeterol inhaled from a single inhaler versus separate inhalers.
PMID 12847476·J Allergy Clin Immunol·2003
4-observational
Aldehyde-sequestering drugs: tools for studying protein damage by lipid peroxidation products.
PMID 12505316·Toxicology·2002
6-review
In vitro antiviral activity of the anthraquinone chrysophanic acid against poliovirus.
PMID 11428243·Antiviral Res·2001
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 165 ROWLAND WAY, #105
NOVATO, CA 94945 - Phone
- (415) 898-7270
Quick Facts
- NPI
- 1366493116
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 1
- Years in Practice
- 34
- Publications
- 20
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