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FRANKLIN BUCKNER, MD
MD
Pediatrics Physician
NPI: 1376562611Individual
Specialties, Licenses & Credentials
Pediatrics PhysicianPrimary
Pediatrics
Code: 208000000X
G18206(CA)
Research & Publications (20)
Identification of three classes of heteroaromatic compounds with activity against intracellular Trypanosoma cruzi by chemical library screening.
PMID 19238193·PLoS Negl Trop Dis·2009
7-preclinical
Buffer optimization of thermal melt assays of Plasmodium proteins for detection of small-molecule ligands.
PMID 19470714·J Biomol Screen·2009
7-preclinical
High-throughput screening of amastigotes of Leishmania donovani clinical isolates against drugs using a colorimetric beta-lactamase assay.
PMID 19634714·Indian J Exp Biol·2009
7-preclinical
Structurally simple inhibitors of lanosterol 14alpha-demethylase are efficacious in a rodent model of acute Chagas disease.
PMID 19463001·J Med Chem·2009
7-preclinical
Altered sterol profile induced in Leishmania amazonensis by a natural dihydroxymethoxylated chalcone.
PMID 19176591·J Antimicrob Chemother·2009
7-preclinical
Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice.
PMID 19296651·J Med Chem·2009
7-preclinical
Rational modification of a candidate cancer drug for use against Chagas disease.
PMID 19239254·J Med Chem·2009
7-preclinical
Sterol 14-demethylase inhibitors for Trypanosoma cruzi infections.
PMID 18365659·Adv Exp Med Biol·2008
6-review
Structure of a Trypanosoma brucei alpha/beta-hydrolase fold protein with unknown function.
PMID 18540054·Acta Crystallogr Sect F Struct Biol Cryst Commun·2008
7-preclinical
Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity.
PMID 18602399·J Mol Biol·2008
7-preclinical
Glycogen synthase kinase 3 is a potential drug target for African trypanosomiasis therapy.
PMID 18644955·Antimicrob Agents Chemother·2008
7-preclinical
Potent, Plasmodium-selective farnesyltransferase inhibitors that arrest the growth of malaria parasites: structure-activity relationships of ethylenediamine-analogue scaffolds and homology model validation.
PMID 18686940·J Med Chem·2008
7-preclinical
Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies.
PMID 18312275·Mol Microbiol·2008
7-preclinical
Genomic-scale prioritization of drug targets: the TDR Targets database.
PMID 18927591·Nat Rev Drug Discov·2008
6-review
Protein geranylgeranyltransferase-I of Trypanosoma cruzi.
PMID 17996962·Mol Biochem Parasitol·2008
7-preclinical
The structure of Plasmodium vivax phosphatidylethanolamine-binding protein suggests a functional motif containing a left-handed helix.
PMID 17329808·Acta Crystallogr Sect F Struct Biol Cryst Commun·2007
4-observational
C-terminal proteolysis of prenylated proteins in trypanosomatids and RNA interference of enzymes required for the post-translational processing pathway of farnesylated proteins.
PMID 17397944·Mol Biochem Parasitol·2007
7-preclinical
Efficacy, pharmacokinetics, and metabolism of tetrahydroquinoline inhibitors of Plasmodium falciparum protein farnesyltransferase.
PMID 17606674·Antimicrob Agents Chemother·2007
7-preclinical
Second generation tetrahydroquinoline-based protein farnesyltransferase inhibitors as antimalarials.
PMID 17722901·J Med Chem·2007
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 4816 PINEVIEW WAY
ANTIOCH, CA 94531 - Phone
- (650) 380-4862
Quick Facts
- NPI
- 1376562611
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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