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MARY STASHKO, N.D. PHD
N.D. PHD
Nutritionist
NPI: 1376976373Individual
Specialties, Licenses & Credentials
NutritionistPrimary
Nutritionist
Code: 133N00000X
Research & Publications (16)
Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit.
PMID 17276063·Bioorg Med Chem Lett·2007
7-preclinical
Discovery of ((4R,5S)-5-amino-4-(2,4,5- trifluorophenyl)cyclohex-1-enyl)-(3- (trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone (ABT-341), a highly potent, selective, orally efficacious, and safe dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.
PMID 17064063·J Med Chem·2006
7-preclinical
Discovery of 2-[4-{{2-(2S,5R)-2-cyano-5-ethynyl-1-pyrrolidinyl]-2-oxoethyl]amino]- 4-methyl-1-piperidinyl]-4-pyridinecarboxylic acid (ABT-279): a very potent, selective, effective, and well-tolerated inhibitor of dipeptidyl peptidase-IV, useful for the treatment of diabetes.
PMID 17034148·J Med Chem·2006
7-preclinical
Crystal structures of DPP-IV (CD26) from rat kidney exhibit flexible accommodation of peptidase-selective inhibitors.
PMID 16768443·Biochemistry·2006
4-observational
Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity.
PMID 16759099·J Med Chem·2006
7-preclinical
Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitors.
PMID 16759095·J Med Chem·2006
7-preclinical
Differentiation of in vitro transcriptional repression and activation profiles of selective glucocorticoid modulators.
PMID 15026058·Bioorg Med Chem Lett·2004
4-observational
Identification of a monoacid-based, cell permeable, selective inhibitor of protein tyrosine phosphatase 1B.
PMID 14592481·Bioorg Med Chem Lett·2003
8-other
Selective protein tyrosine phosphatase 1B inhibitors: targeting the second phosphotyrosine binding site with non-carboxylic acid-containing ligands.
PMID 12877578·J Med Chem·2003
8-other
Potent, selective inhibitors of protein tyrosine phosphatase 1B.
PMID 12749891·Bioorg Med Chem Lett·2003
8-other
Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B.
PMID 12747781·J Med Chem·2003
7-preclinical
Discovery of a potent, selective protein tyrosine phosphatase 1B inhibitor using a linked-fragment strategy.
PMID 12670229·J Am Chem Soc·2003
8-other
Nonsteroidal selective glucocorticoid modulators: the effect of C-10 substitution on receptor selectivity and functional potency of 5-allyl-2,5-dihydro-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines.
PMID 12620078·J Med Chem·2003
7-preclinical
trans-Activation and repression properties of the novel nonsteroid glucocorticoid receptor ligand 2,5-dihydro-9-hydroxy-10-methoxy-2,2,4-trimethyl-5-(1-methylcyclohexen-3-y1)-1H-[1]benzopyrano[3,4-f]quinoline (A276575) and its four stereoisomers.
PMID 12130681·Mol Pharmacol·2002
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 2913 MAIN RD E
EMMAUS, PA 18049 - Phone
- (610) 965-8132
Quick Facts
- NPI
- 1376976373
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 16
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