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JAKUB POLAKOWSKI, PHARMD
PHARMD
Pharmacist
NPI: 1396379848Individual
Specialties, Licenses & Credentials
PharmacistPrimary
Pharmacist
Code: 183500000X
19228-40(WI)
Research & Publications (20)
Tetrahydropyridine-4-carboxamides as novel, potent transient receptor potential vanilloid 1 (TRPV1) antagonists.
PMID 18722778·Bioorg Med Chem·2008
7-preclinical
Evoked changes in cardiovascular function in rats by infusion of levosimendan, OR-1896 [(R)-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)acetamide], OR-1855 [(R)-6-(4-aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one], dobutamine, and milrinone: comparative effects on peripheral resistance, cardiac output, dP/dt, pulse rate, and blood pressure.
PMID 18171907·J Pharmacol Exp Ther·2008
4-observational
Comparative effects of levosimendan, OR-1896, OR-1855, dobutamine, and milrinone on vascular resistance, indexes of cardiac function, and O2 consumption in dogs.
PMID 17982006·Am J Physiol Heart Circ Physiol·2008
4-observational
Hemodynamic effects of potent and selective JNK inhibitors in anesthetized rats: implication for targeting protein kinases in metabolic diseases.
PMID 17055723·Bioorg Med Chem Lett·2007
7-preclinical
Syntheses of potent, selective, and orally bioavailable indazole-pyridine series of protein kinase B/Akt inhibitors with reduced hypotension.
PMID 17523610·J Med Chem·2007
7-preclinical
Optimization of chromone-2-carboxamide melanin concentrating hormone receptor 1 antagonists: assessment of potency, efficacy, and cardiovascular safety.
PMID 17064075·J Med Chem·2006
7-preclinical
Discovery of 2-[4-{{2-(2S,5R)-2-cyano-5-ethynyl-1-pyrrolidinyl]-2-oxoethyl]amino]- 4-methyl-1-piperidinyl]-4-pyridinecarboxylic acid (ABT-279): a very potent, selective, effective, and well-tolerated inhibitor of dipeptidyl peptidase-IV, useful for the treatment of diabetes.
PMID 17034148·J Med Chem·2006
7-preclinical
Differential effects of n-3 polyunsaturated fatty acids on metabolic control and vascular reactivity in the type 2 diabetic ob/ob mouse.
PMID 16979408·Metabolism·2006
7-preclinical
Structure-activity studies of a novel series of 5,6-fused heteroaromatic ureas as TRPV1 antagonists.
PMID 16621571·Bioorg Med Chem·2006
7-preclinical
Screening for cardiovascular safety: a structure-activity approach for guiding lead selection of melanin concentrating hormone receptor 1 antagonists.
PMID 16570930·J Med Chem·2006
7-preclinical
Predictive, non-GLP models of secondary pharmacodynamics: putting the best compounds forward.
PMID 15950522·Curr Opin Chem Biol·2005
6-review
Postischemic administration of CGX-1051, a peptide from cone snail venom, reduces infarct size in both rat and dog models of myocardial ischemia and reperfusion.
PMID 16044024·J Cardiovasc Pharmacol·2005
7-preclinical
Effects of selective dopamine receptor subtype agonists on cardiac contractility and regional haemodynamics in rats.
PMID 15659045·Clin Exp Pharmacol Physiol·2004
4-observational
Tumor selective antivascular effects of the novel antimitotic compound ABT-751: an in vivo rat regional hemodynamic study.
PMID 15173957·Cancer Chemother Pharmacol·2004
7-preclinical
Activation of dopamine D4 receptors by ABT-724 induces penile erection in rats.
PMID 15087502·Proc Natl Acad Sci U S A·2004
7-preclinical
Preischemic and postischemic administration of AEOL10113 reduces infarct size in a rat model of myocardial ischemia and reperfusion.
PMID 12717101·J Cardiovasc Pharmacol·2003
7-preclinical
K-ATP opener-mediated attenuation of spontaneous bladder contractions in ligature-intact, partial bladder outlet obstructed rats.
PMID 12597992·Life Sci·2003
7-preclinical
A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat.
PMID 12482951·Proc Natl Acad Sci U S A·2002
7-preclinical
Analgesic and anti-inflammatory effects of A-286501, a novel orally active adenosine kinase inhibitor.
PMID 11932067·Pain·2002
7-preclinical
Oral bimoclomol elevates heat shock protein 70 and reduces myocardial infarct size in rats.
PMID 11790381·Eur J Pharmacol·2002
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
Via practice · 2 locations total
- Address
- 3601 BEE RIDGE RD
SARASOTA, FL 34233 - Phone
- (941) 921-4681
Quick Facts
- NPI
- 1396379848
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 2
- Publications
- 20
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