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DONALD KUFE, M.D.
M.D.
Hematology & Oncology Physician
NPI: 1396953238Individual
Specialties, Licenses & Credentials
Hematology & Oncology PhysicianPrimary
Internal Medicine — Hematology & Oncology
Code: 207RH0003X
41308(MA)
Research & Publications (20)
Functional targeting of the MUC1 oncogene in human cancers.
PMID 19556858·Cancer Biol Ther·2009
6-review
Targeting the human MUC1 oncoprotein: a tale of two proteins.
PMID 18347419·Cancer Biol Ther·2008
7-preclinical
MUC1-induced alterations in a lipid metabolic gene network predict response of human breast cancers to tamoxifen treatment.
PMID 19289846·Proc Natl Acad Sci U S A·2009
8-other
Direct targeting of the mucin 1 oncoprotein blocks survival and tumorigenicity of human breast carcinoma cells.
PMID 19491255·Cancer Res·2009
7-preclinical
MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation.
PMID 19424588·Int J Oncol·2009
8-other
MUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancer.
PMID 19318547·Cancer Res·2009
7-preclinical
Translation of the radio- and chemo-inducible TNFerade vector to the treatment of human cancers.
PMID 19444302·Cancer Gene Ther·2009
8-other
Translational strategies exploiting TNF-alpha that sensitize tumors to radiation therapy.
PMID 18974777·Cancer Gene Ther·2009
7-preclinical
MUC1 oncoprotein suppresses activation of the ARF-MDM2-p53 pathway.
PMID 18981727·Cancer Biol Ther·2008
8-other
MUC1 oncoprotein promotes growth and survival of human multiple myeloma cells.
PMID 18575761·Int J Oncol·2008
8-other
Triterpenoid CDDO-methyl ester inhibits the Janus-activated kinase-1 (JAK1)-->signal transducer and activator of transcription-3 (STAT3) pathway by direct inhibition of JAK1 and STAT3.
PMID 18413761·Cancer Res·2008
8-other
MUC1 oncoprotein blocks death receptor-mediated apoptosis by inhibiting recruitment of caspase-8.
PMID 18676836·Cancer Res·2008
8-other
Fusions of dendritic cells with breast carcinoma stimulate the expansion of regulatory T cells while concomitant exposure to IL-12, CpG oligodeoxynucleotides, and anti-CD3/CD28 promotes the expansion of activated tumor reactive cells.
PMID 18566447·J Immunol·2008
8-other
Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding.
PMID 17638900·Cancer Res·2007
8-other
The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loop.
PMID 17889671·Mol Cell·2007
7-preclinical
MUC1 oncoprotein regulates Bcr-Abl stability and pathogenesis in chronic myelogenous leukemia cells.
PMID 18089786·Cancer Res·2007
8-other
Diverse TNFalpha-induced death pathways are enhanced by inhibition of NF-kappaB.
PMID 17982679·Int J Oncol·2007
8-other
Phase I/II study of vaccination with electrofused allogeneic dendritic cells/autologous tumor-derived cells in patients with stage IV renal cell carcinoma.
PMID 17893567·J Immunother·2007
3-trial
MUC1 oncoprotein activates the IkappaB kinase beta complex and constitutive NF-kappaB signalling.
PMID 18037881·Nat Cell Biol·2007
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 450 BROOKLINE AVE, D830
BOSTON, MA 02215 - Phone
- (617) 632-3141
Quick Facts
- NPI
- 1396953238
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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