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DAVID TORTORELLA, M.D.
M.D.
Public Health & General Preventive Medicine Physician
NPI: 1417139700Individual
Specialties, Licenses & Credentials
Addiction Medicine (Internal Medicine) Physician
Internal Medicine — Addiction Medicine
Code: 207RA0401X
246763(MA)
Pediatrics Physician
Pediatrics
Code: 208000000X
246763(MA)
Obesity Medicine (Preventive Medicine) Physician
Preventive Medicine — Obesity Medicine
Code: 2083B0002X
246763(MA)
Public Health & General Preventive Medicine PhysicianPrimary
Preventive Medicine — Public Health & General Preventive Medicine
Code: 2083P0901X
246763(MA)
Research & Publications (20)
Down-regulation of MHC class I antigen presentation by HCMV; lessons for tumor immunology.
PMID 10854174·Immunol Invest·2000
6-review
Cln6 mutants associated with neuronal ceroid lipofuscinosis are degraded in a proteasome-dependent manner.
PMID 18811591·Biosci Rep·2009
8-other
Human cytomegalovirus-encoded immune modulators partner to downregulate major histocompatibility complex class I molecules.
PMID 19004944·J Virol·2009
8-other
TRAM1 participates in human cytomegalovirus US2- and US11-mediated dislocation of an endoplasmic reticulum membrane glycoprotein.
PMID 19121997·J Biol Chem·2009
8-other
Endoplasmic reticulum chaperones participate in human cytomegalovirus US2-mediated degradation of class I major histocompatibility complex molecules.
PMID 18420789·J Gen Virol·2008
8-other
A bipartite trigger for dislocation directs the proteasomal degradation of an endoplasmic reticulum membrane glycoprotein.
PMID 18086679·J Biol Chem·2008
8-other
Cold neutron energy dependent production of ultracold neutrons in solid deuterium.
PMID 18233572·Phys Rev Lett·2007
8-other
Dislocation of an endoplasmic reticulum membrane glycoprotein involves the formation of partially dislocated ubiquitinated polypeptides.
PMID 17650499·J Biol Chem·2007
8-other
Signal peptide peptidase is required for dislocation from the endoplasmic reticulum.
PMID 16738546·Nature·2006
8-other
A structural determinant of human cytomegalovirus US2 dictates the down-regulation of class I major histocompatibility molecules.
PMID 16687410·J Biol Chem·2006
8-other
Cotranslational endoplasmic reticulum assembly of FcepsilonRI controls the formation of functional IgE-binding receptors.
PMID 15642744·J Exp Med·2005
8-other
A glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised.
PMID 14749736·EMBO J·2004
8-other
Dissection of the dislocation pathway for type I membrane proteins with a new small molecule inhibitor, eeyarestatin.
PMID 14767067·Mol Biol Cell·2004
8-other
Dislocation of a type I membrane protein requires interactions between membrane-spanning segments within the lipid bilayer.
PMID 12972557·Mol Biol Cell·2003
7-preclinical
Ubiquitinylation of the cytosolic domain of a type I membrane protein is not required to initiate its dislocation from the endoplasmic reticulum.
PMID 12832421·J Biol Chem·2003
7-preclinical
Protein unfolding is not a prerequisite for endoplasmic reticulum-to-cytosol dislocation.
PMID 12482753·J Biol Chem·2003
8-other
The human cytomegalovirus US10 gene product delays trafficking of major histocompatibility complex class I molecules.
PMID 12388737·J Virol·2002
8-other
Human cytomegalovirus gene products US2 and US11 differ in their ability to attack major histocompatibility class I heavy chains in dendritic cells.
PMID 11967320·J Virol·2002
8-other
Visualization of the ER-to-cytosol dislocation reaction of a type I membrane protein.
PMID 11867532·EMBO J·2002
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
Via practice · 2 locations total
- Address
- 47 CONGRESS ST
SALEM, MA 01970 - Phone
- (978) 744-8388
Quick Facts
- NPI
- 1417139700
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 4
- Locations
- 2
- Publications
- 20
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