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MEREDITH JOSEPHS, M.D.
M.D.
Family Medicine Physician
NPI: 1417946658Individual
Specialties, Licenses & Credentials
Family Medicine PhysicianPrimary
Family Medicine
Code: 207Q00000X
MD31056(MD)
Research & Publications (13)
Structural insights into formation of an active signaling complex between Rac and phospholipase C gamma 2.
PMID 19394299·Mol Cell·2009
8-other
In vitro reconstitution of activation of PLCepsilon by Ras and Rho GTPases.
PMID 19160682·Methods Mol Biol·2009
7-preclinical
rac regulates its effector phospholipase Cgamma2 through interaction with a split pleckstrin homology domain.
PMID 18728011·J Biol Chem·2008
7-preclinical
Structural and mechanistic insights into ras association domains of phospholipase C epsilon.
PMID 16483931·Mol Cell·2006
7-preclinical
Autoimmunity and inflammation due to a gain-of-function mutation in phospholipase C gamma 2 that specifically increases external Ca2+ entry.
PMID 15845450·Immunity·2005
7-preclinical
Irreversible inactivation of magnesium-dependent neutral sphingomyelinase 1 (NSM1) by peroxynitrite, a nitric oxide-derived oxidant.
PMID 12417336·FEBS Lett·2002
7-preclinical
Biochemical identification of a neutral sphingomyelinase 1 (NSM1)-like enzyme as the major NSM activity in the DT40 B-cell line: absence of a role in the apoptotic response to endoplasmic reticulum stress.
PMID 12071841·Biochem J·2002
4-observational
Sequence analysis identifies TTRAP, a protein that associates with CD40 and TNF receptor-associated factors, as a member of a superfamily of divalent cation-dependent phosphodiesterases.
PMID 11478795·Biochem Biophys Res Commun·2001
7-preclinical
Hypotensive resuscitation using a polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201) leads to reversal of anaerobic metabolism.
PMID 11426122·J Trauma·2001
3-trial
Structural requirements for catalysis and membrane targeting of mammalian enzymes with neutral sphingomyelinase and lysophospholipid phospholipase C activities. Analysis by chemical modification and site-directed mutagenesis.
PMID 10871611·J Biol Chem·2000
7-preclinical
Lipopolysaccharide and D-galactosamine-induced hepatic injury is mediated by TNF-alpha and not by Fas ligand.
PMID 10801287·Am J Physiol Regul Integr Comp Physiol·2000
7-preclinical
Modulation of the acute phase response by altered expression of the IL-1 type 1 receptor or IL-1ra.
PMID 10749768·Am J Physiol Regul Integr Comp Physiol·2000
7-preclinical
A neutral magnesium-dependent sphingomyelinase isoform associated with intracellular membranes and reversibly inhibited by reactive oxygen species.
PMID 10625655·J Biol Chem·2000
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 2831 15TH ST NW
WASHINGTON, DC 20009 - Phone
- (202) 462-4788
Quick Facts
- NPI
- 1417946658
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 13
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