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LEILA OBEID, M.D.
M.D.
Internal Medicine Physician
NPI: 1427012939IndividualAccepts Medicare
Specialties, Licenses & Credentials
Internal Medicine PhysicianPrimary
Internal Medicine
Code: 207R00000X
MD459217(PA)
CMS Specialties
PrimaryINTERNAL MEDICINE
Education
LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE IN NEW ORLEANS
Class of 2002
Research & Publications (20)
Sphingosine kinase 1 is up-regulated during hypoxia in U87MG glioma cells. Role of hypoxia-inducible factors 1 and 2.
PMID 18055454·J Biol Chem·2008
8-other
AMPK inhibitor Compound C stimulates ceramide production and promotes Bax redistribution and apoptosis in MCF7 breast carcinoma cells.
PMID 19528633·J Lipid Res·2009
8-other
Acid beta-glucosidase 1 counteracts p38delta-dependent induction of interleukin-6: possible role for ceramide as an anti-inflammatory lipid.
PMID 19279008·J Biol Chem·2009
8-other
Involvement of acid beta-glucosidase 1 in the salvage pathway of ceramide formation.
PMID 19279011·J Biol Chem·2009
8-other
A role for sphingosine kinase 1 in dextran sulfate sodium-induced colitis.
PMID 18815359·FASEB J·2009
7-preclinical
Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells.
PMID 19137010·Oncogene·2009
8-other
ISC1-dependent metabolic adaptation reveals an indispensable role for mitochondria in induction of nuclear genes during the diauxic shift in Saccharomyces cerevisiae.
PMID 19179331·J Biol Chem·2009
7-preclinical
Alkaline ceramidase 2 regulates beta1 integrin maturation and cell adhesion.
PMID 18945876·FASEB J·2009
8-other
Dual and distinct roles for sphingosine kinase 1 and sphingosine 1 phosphate in the response to inflammatory stimuli in RAW macrophages.
PMID 18166496·Prostaglandins Other Lipid Mediat·2008
7-preclinical
Molecular targeting of acid ceramidase: implications to cancer therapy.
PMID 18691012·Curr Drug Targets·2008
6-review
De novo N-palmitoylsphingosine synthesis is the major biochemical mechanism of ceramide accumulation following p53 up-regulation.
PMID 18400537·Prostaglandins Other Lipid Mediat·2008
8-other
Ceramide generated by sphingomyelin hydrolysis and the salvage pathway is involved in hypoxia/reoxygenation-induced Bax redistribution to mitochondria in NT-2 cells.
PMID 18676372·J Biol Chem·2008
8-other
A novel role for protein kinase Cdelta-mediated phosphorylation of acid sphingomyelinase in UV light-induced mitochondrial injury.
PMID 17698617·FASEB J·2008
8-other
Principles of bioactive lipid signalling: lessons from sphingolipids.
PMID 18216770·Nat Rev Mol Cell Biol·2008
6-review
Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes.
PMID 17713573·J Invest Dermatol·2008
8-other
Hyaluronan constitutively regulates activation of COX-2-mediated cell survival activity in intestinal epithelial and colon carcinoma cells.
PMID 18326857·J Biol Chem·2008
8-other
Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate.
PMID 18619555·Biochim Biophys Acta·2008
6-review
Long-chain ceramide is a potent inhibitor of the mitochondrial permeability transition pore.
PMID 18596045·J Biol Chem·2008
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 306 E LANCASTER AVE STE 300
WYNNEWOOD, PA 19096 - Phone
- (484) 476-7255
Quick Facts
- NPI
- 1427012939
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 1
- Years in Practice
- 24
- Publications
- 20
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