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JOSE BREA, MD
MD
Surgery Physician
NPI: 1447236724Individual
Specialties, Licenses & Credentials
Surgery PhysicianPrimary
Surgery
Code: 208600000X
4726(PR)
Research & Publications (20)
Chitosan-hyaluronic acid nanoparticles loaded with heparin for the treatment of asthma.
PMID 19467809·Int J Pharm·2009
7-preclinical
1,3-dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships.
PMID 19398343·Bioorg Med Chem·2009
7-preclinical
Synthesis of novel 1-alkyl-8-substituted-3-(3-methoxypropyl) xanthines as putative A(2B) receptor antagonists.
PMID 19346133·Bioorg Med Chem·2009
8-other
Evidence for distinct antagonist-revealed functional states of 5-hydroxytryptamine(2A) receptor homodimers.
PMID 19279328·Mol Pharmacol·2009
7-preclinical
Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands.
PMID 19217777·Bioorg Med Chem Lett·2009
8-other
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships.
PMID 18938084·Bioorg Med Chem·2008
7-preclinical
Synthesis, binding affinity, and molecular docking analysis of new benzofuranone derivatives as potential antipsychotics.
PMID 18783204·J Med Chem·2008
8-other
A new chemical tool (C0036E08) supports the role of adenosine A(2B) receptors in mediating human mast cell activation.
PMID 18687311·Biochem Pharmacol·2008
7-preclinical
Synthesis of new mannosyl, galactosyl and glucosyl theophylline nucleosides with potential activity as antagonists of adenosine receptors. DEMA-induced cyclization of glycosylideneiminouracils.
PMID 18275941·Carbohydr Res·2008
8-other
Synthesis, adenosine receptor binding and 3D-QSAR of 4-substituted 2-(2'-furyl)-1,2,4-triazolo[1,5-a]quinoxalines.
PMID 18249548·Bioorg Med Chem·2008
8-other
1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor.
PMID 18226909·Bioorg Med Chem·2008
8-other
Synthesis and binding affinity of new pyrazole and isoxazole derivatives as potential atypical antipsychotics.
PMID 17588750·Bioorg Med Chem Lett·2007
8-other
Multistructure 3D-QSAR studies on a series of conformationally constrained butyrophenones docked into a new homology model of the 5-HT2A receptor.
PMID 17579386·J Med Chem·2007
8-other
Synthesis and evaluation of adenosine antagonist activity of a series of [1,2,4]triazolo[1,5-c]quinazolines.
PMID 17329874·Chem Pharm Bull (Tokyo)·2007
8-other
Parallel regulation by olanzapine of the patterns of expression of 5-HT2A and D3 receptors in rat central nervous system and blood cells.
PMID 16905159·Neuropharmacology·2006
4-observational
Measuring direction in the coupling of biological oscillators: a case study for electroreceptors of paddlefish.
PMID 16822043·Chaos·2006
7-preclinical
QF2004B, a potential antipsychotic butyrophenone derivative with similar pharmacological properties to clozapine.
PMID 16697427·Neuropharmacology·2006
4-observational
Synthesis and binding affinity of novel 3-aminoethyl-1-tetralones, potential atypical antipsychotics.
PMID 15878662·Bioorg Med Chem Lett·2005
4-observational
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- ADMINISTRACION DE SERVICIOS MEDICOS DE PR, BOX 2129
SAN JUAN, PR 00926 - Phone
- (787) 777-3535
Quick Facts
- NPI
- 1447236724
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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