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FRANK TUCCI, M.D.
M.D.
Internal Medicine Physician
NPI: 1457622979Individual
Specialties, Licenses & Credentials
Internal Medicine PhysicianPrimary
Internal Medicine
Code: 207R00000X
MD094138-1(NY)
Research & Publications (20)
Characterization of novel selective H1-antihistamines for clinical evaluation in the treatment of insomnia.
PMID 19663387·J Med Chem·2009
7-preclinical
Discovery of sodium R-(+)-4-{2-[5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-[trifluoromethyl]benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenylethylamino}butyrate (elagolix), a potent and orally available nonpeptide antagonist of the human gonadotropin-releasing hormone receptor.
PMID 19006286·J Med Chem·2008
7-preclinical
5-Aryluracils as potent GnRH antagonists-Characterization of atropisomers.
PMID 18442905·Bioorg Med Chem Lett·2008
8-other
Current and emerging therapeutic approaches in HCV-related mixed cryoglobulinemia.
PMID 18220767·Curr Med Chem·2008
6-review
Increased serum levels of the chemokine CXCL13 and up-regulation of its gene expression are distinctive features of HCV-related cryoglobulinemia and correlate with active cutaneous vasculitis.
PMID 18550853·Blood·2008
8-other
Design and synthesis of 3-arylpyrrolidine-2-carboxamide derivatives as melanocortin-4 receptor ligands.
PMID 18294847·Bioorg Med Chem Lett·2008
7-preclinical
Structure-activity relationship studies on a series of piperazinebenzylalcohols and their ketone and amine analogs as melanocortin-4 receptor ligands.
PMID 18682322·Bioorg Med Chem Lett·2008
4-observational
Studies on the structure-activity relationship of the basic amine of phenylpiperazines as melanocortin-4 receptor antagonists.
PMID 18220971·Med Chem·2008
7-preclinical
Pharmacological and pharmacokinetic characterization of 2-piperazine-alpha-isopropyl benzylamine derivatives as melanocortin-4 receptor antagonists.
PMID 18417348·Bioorg Med Chem·2008
7-preclinical
Syntheses of tetrahydrothiophenes and tetrahydrofurans and studies of their derivatives as melanocortin-4 receptor ligands.
PMID 18082401·Bioorg Med Chem Lett·2008
8-other
Identification and characterization of pyrrolidine diastereoisomers as potent functional agonists and antagonists of the human melanocortin-4 receptor.
PMID 18032040·Bioorg Med Chem Lett·2008
7-preclinical
Potent and orally bioavailable zwitterion GnRH antagonists with low CYP3A4 inhibitory activity.
PMID 18442910·Bioorg Med Chem Lett·2008
7-preclinical
Pyrrolidinones as potent functional antagonists of the human melanocortin-4 receptor.
PMID 17822895·Bioorg Med Chem Lett·2007
7-preclinical
Discovery of 1-[2-[(1S)-(3-dimethylaminopropionyl)amino-2-methylpropyl]-4-methylphenyl]-4-[(2R)-methyl-3-(4-chlorophenyl)-propionyl]piperazine as an orally active antagonist of the melanocortin-4 receptor for the potential treatment of cachexia.
PMID 17918824·J Med Chem·2007
4-observational
Synthesis and characterization of pyrrolidine derivatives as potent agonists of the human melanocortin-4 receptor.
PMID 17933528·Bioorg Med Chem Lett·2007
4-observational
Synthesis and characterization of trans-4-(4-chlorophenyl)pyrrolidine-3-carboxamides of piperazinecyclohexanes as ligands for the melanocortin-4 receptor.
PMID 17964151·Bioorg Med Chem Lett·2007
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 45 OLD HOMESTEAD ROAD
PORT JEFFERSON, NY 11777 - Phone
- (631) 928-1813
Quick Facts
- NPI
- 1457622979
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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