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LEONARD FIUME, D.M.D.
D.M.D.
Orthodontics and Dentofacial Orthopedics Dentistry
NPI: 1477961654Individual
Specialties, Licenses & Credentials
Orthodontics and Dentofacial Orthopedics DentistryPrimary
Dentist — Orthodontics and Dentofacial Orthopedics
Code: 1223X0400X
9765(NC)
Research & Publications (20)
Detection of Legionella pneumophila in water samples by species-specific real-time and nested PCR assays.
PMID 16305672·Lett Appl Microbiol·2005
8-other
The enhancement of interstitial transport of a doxorubicin-lactosaminated albumin conjugate by imatinib: in rat hepatocellular carcinoma it is not preferentially higher than that in liver and bone marrow.
PMID 19572414·Eur J Pharm Biopharm·2009
4-observational
Doxorubicin coupled to lactosaminated human albumin: a hepatocellular carcinoma targeted drug.
PMID 18755287·Drug Discov Today·2008
7-preclinical
Binding of the doxorubicin-lactosaminated human albumin conjugate to HCC cells is mediated by the drug moieties.
PMID 18606580·Dig Liver Dis·2008
7-preclinical
Doxorubicin coupled to lactosaminated albumin: effect of heterogeneity in drug load on conjugate disposition and hepatocellular carcinoma uptake in rats.
PMID 18201877·Eur J Pharm Sci·2008
7-preclinical
Efficacy of doxorubicin coupled to lactosaminated albumin on rat hepatocellular carcinomas evaluated by ultrasound imaging.
PMID 18054847·Dig Liver Dis·2008
7-preclinical
Coupling of lactose molecules to the carrier protein hinders the spleen and bone marrow uptake of doxorubicin conjugated with human albumin.
PMID 17218086·Eur J Pharm Sci·2007
7-preclinical
A conjugate of doxorubicin with lactosaminated albumin enhances the drug concentrations in all the forms of rat hepatocellular carcinomas independently of their differentiation grade.
PMID 16842330·Liver Int·2006
7-preclinical
Doxorubicin coupled to lactosaminated albumin: Effects on rats with liver fibrosis and cirrhosis.
PMID 16595196·Dig Liver Dis·2006
4-observational
Doxorubicin coupled to lactosaminated albumin: enhanced drug levels in rat hepatocarcinomas.
PMID 16364702·Dig Liver Dis·2006
7-preclinical
Doxorubicin coupled to lactosaminated albumin inhibits the growth of hepatocellular carcinomas induced in rats by diethylnitrosamine.
PMID 16023760·J Hepatol·2005
7-preclinical
Enhanced uptake of lactosaminated human albumin by rat hepatocarcinomas: implications for an improved chemotherapy of primary liver tumors.
PMID 15998437·Liver Int·2005
7-preclinical
A novel method for coupling doxorubicin to lactosaminated human albumin by an acid sensitive hydrazone bond: synthesis, characterization and preliminary biological properties of the conjugate.
PMID 15567293·Eur J Pharm Sci·2004
7-preclinical
Liver-targeted doxorubicin: effects on rat regenerating hepatocytes.
PMID 15189276·Liver Int·2004
7-preclinical
Synthesis and physicochemical characteristics of a liver-targeted conjugate of fluorodeoxyuridine monophosphate with lactosaminated human albumin.
PMID 14608620·Rapid Commun Mass Spectrom·2003
8-other
Doxorubicin coupled to lactosaminated human albumin remains confined within mouse liver cells after the intracellular release from the carrier.
PMID 12868680·Dig Liver Dis·2003
7-preclinical
Floxuridine coupling with lactosaminated human albumin to increase drug efficacy on liver micrometastases.
PMID 12132792·Dig Liver Dis·2002
7-preclinical
Conjugates of nucleoside analogs with lactosaminated human albumin to selectively increase the drug levels in liver blood: requirements for a regional chemotherapy.
PMID 11961068·J Pharmacol Exp Ther·2002
7-preclinical
Coupling of 5-fluoro 2'-deoxyuridine to lactosaminated poly-l-lysine: an approach to a regional, non-invasive chemotherapy of liver micrometastases.
PMID 11226380·Biochem Pharmacol·2001
7-preclinical
Enhanced liver blood concentrations of adenine arabinoside accomplished by lactosaminated poly-L-lysine coupling: implications for regional chemotherapy of hepatic micrometastases.
PMID 10609559·Biochem Pharmacol·2000
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 608 MCCARTHY BLVD.
NEW BERN, NC 28562 - Phone
- (252) 636-1900
Quick Facts
- NPI
- 1477961654
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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