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LYNN STREET, MD
MD
Internal Medicine Physician
NPI: 1487609160Individual
Specialties, Licenses & Credentials
Internal Medicine PhysicianPrimary
Internal Medicine
Code: 207R00000X
031188(CT)
Research & Publications (20)
Optimisation of a series of potent, selective and orally bioavailable GlyT1 inhibitors.
PMID 19318248·Bioorg Med Chem Lett·2009
4-observational
2,3,7-Trisubstituted pyrazolo[1,5-d][1,2,4]triazines: functionally selective GABAA alpha3-subtype agonists.
PMID 16621541·Bioorg Med Chem Lett·2006
8-other
Discovery of imidazo[1,2-b][1,2,4]triazines as GABA(A) alpha2/3 subtype selective agonists for the treatment of anxiety.
PMID 16480260·J Med Chem·2006
7-preclinical
Imidazo[1,2-a]pyrimidines as functionally selective GABA(A) ligands.
PMID 16406613·Bioorg Med Chem Lett·2006
8-other
Imidazo[1,2-a]pyrimidines as functionally selective and orally bioavailable GABA(A)alpha2/alpha3 binding site agonists for the treatment of anxiety disorders.
PMID 16392789·J Med Chem·2006
7-preclinical
Imidazo[1,2-b][1,2,4]triazines as alpha2/alpha3 subtype selective GABA A agonists for the treatment of anxiety.
PMID 16386900·Bioorg Med Chem Lett·2006
7-preclinical
Imidazo[1,2-a]pyrazin-8-ones, imidazo[1,2-d][1,2,4]triazin-8-ones and imidazo[2,1-f][1,2,4]triazin-8-ones as alpha2/alpha3 subtype selective GABA A agonists for the treatment of anxiety.
PMID 16384707·Bioorg Med Chem Lett·2006
7-preclinical
Spectroscopic phase-dispersion optical coherence tomography measurements of scattering phantoms.
PMID 19529186·Opt Express·2006
8-other
TPA023 [7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine], an agonist selective for alpha2- and alpha3-containing GABAA receptors, is a nonsedating anxiolytic in rodents and primates.
PMID 16183706·J Pharmacol Exp Ther·2006
7-preclinical
7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine: a functionally selective gamma-aminobutyric acid(A) (GABA(A)) alpha2/alpha3-subtype selective agonist that exhibits potent anxiolytic activity but is not sedating in animal models.
PMID 16279764·J Med Chem·2005
7-preclinical
Pyrazolopyridinones as functionally selective GABAA ligands.
PMID 16153832·Bioorg Med Chem Lett·2005
8-other
Evidence for a significant role of alpha 3-containing GABAA receptors in mediating the anxiolytic effects of benzodiazepines.
PMID 16291941·J Neurosci·2005
4-observational
Synthesis and biological evaluation of 3-heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazines and analogues as subtype-selective inverse agonists for the GABA(A)alpha5 benzodiazepine binding site.
PMID 15214791·J Med Chem·2004
7-preclinical
2,5-Dihydropyrazolo[4,3-c]pyridin-3-ones: functionally selective benzodiazepine binding site ligands on the GABAA receptor.
PMID 15177449·Bioorg Med Chem Lett·2004
7-preclinical
Report of the National Institutes of Health workshop on overcoming barriers to treatment research in anorexia nervosa.
PMID 15101067·Int J Eat Disord·2004
8-other
Selective, orally active gamma-aminobutyric acidA alpha5 receptor inverse agonists as cognition enhancers.
PMID 15084116·J Med Chem·2004
7-preclinical
3-phenyl-6-(2-pyridyl)methyloxy-1,2,4-triazolo[3,4-a]phthalazines and analogues: high-affinity gamma-aminobutyric acid-A benzodiazepine receptor ligands with alpha 2, alpha 3, and alpha 5-subtype binding selectivity over alpha 1.
PMID 15027873·J Med Chem·2004
7-preclinical
Tricyclic pyridones as functionally selective human GABAA alpha 2/3 receptor-ion channel ligands.
PMID 15026049·Bioorg Med Chem Lett·2004
8-other
Subtype-selective GABAergic drugs facilitate extinction of mouse operant behaviour.
PMID 14680756·Neuropharmacology·2004
4-observational
Subdomain organization and catalytic residues of the F factor TraI relaxase domain.
PMID 12637015·Biochim Biophys Acta·2003
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 100 YORK ST, SUITE 2E
NEW HAVEN, CT 06511 - Phone
- (203) 787-3588
Quick Facts
- NPI
- 1487609160
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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