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SHARRON LAPLANTE, MD
MD
General Practice Physician
NPI: 1497065163Individual
Specialties, Licenses & Credentials
General Practice PhysicianPrimary
General Practice
Code: 208D00000X
027074(CT)
Research & Publications (17)
The use of chemical double-mutant cycles in biomolecular recognition studies: application to HCV NS3 protease inhibitors.
PMID 18942693·ChemMedChem·2008
8-other
Scaffold hopping in the rational design of novel HIV-1 non-nucleoside reverse transcriptase inhibitors.
PMID 17451954·Bioorg Med Chem Lett·2007
8-other
Seasonal and geographical variations of sterol composition in snow crab hepatopancreas and pelagic fish viscera from Eastern Quebec.
PMID 17374564·Comp Biochem Physiol B Biochem Mol Biol·2007
4-observational
Quantifying trifluoroacetic acid as a counterion in drug discovery by 19F NMR and capillary electrophoresis.
PMID 17145157·J Pharm Biomed Anal·2007
4-observational
Improved replicon cellular activity of non-nucleoside allosteric inhibitors of HCV NS5B polymerase: from benzimidazole to indole scaffolds.
PMID 16908138·Bioorg Med Chem Lett·2006
8-other
RCM of tripeptide dienes containing a chiral vinylcyclopropane moiety: impact of different Ru-based catalysts on the stereochemical integrity of the macrocyclic products.
PMID 16355998·J Org Chem·2005
8-other
Binding mode determination of benzimidazole inhibitors of the hepatitis C virus RNA polymerase by a structure and dynamics strategy.
PMID 15368379·Angew Chem Int Ed Engl·2004
8-other
Changes in drug 13C NMR chemical shifts as a tool for monitoring interactions with DNA.
PMID 15110931·Biophys Chem·2004
4-observational
Specific inhibitors of HCV polymerase identified using an NS5B with lower affinity for template/primer substrate.
PMID 14739234·Nucleic Acids Res·2004
7-preclinical
Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery and preliminary SAR of benzimidazole derivatives.
PMID 14684311·Bioorg Med Chem Lett·2004
8-other
An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus.
PMID 14578911·Nature·2003
3-trial
Macrocyclic inhibitors of the NS3 protease as potential therapeutic agents of hepatitis C virus infection.
PMID 12671967·Angew Chem Int Ed Engl·2003
8-other
Randomized phase III study of fludarabine phosphate versus cyclophosphamide, vincristine, and prednisone in patients with recurrent low-grade non-Hodgkin's lymphoma previously treated with an alkylating agent or alkylator-containing regimen.
PMID 12488409·J Clin Oncol·2002
3-trial
Changes in 13C NMR chemical shifts of DNA as a tool for monitoring drug interactions.
PMID 11407640·Biophys Chem·2001
8-other
Circumstances leading to a change to prone sleeping in sudden infant death syndrome victims.
PMID 11099629·Pediatrics·2000
8-other
NMR line-broadening and transferred NOESY as a medicinal chemistry tool for studying inhibitors of the hepatitis C virus NS3 protease domain.
PMID 11055336·Bioorg Med Chem Lett·2000
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 177 WESTON STREET
HARTFORD, CT 06120 - Phone
- (860) 240-1840
Quick Facts
- NPI
- 1497065163
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 17
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