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MARINA KONOPLEVA, M.D. PHD
M.D. PHD
Hematology & Oncology Physician
NPI: 1518063486Individual
Specialties, Licenses & Credentials
Hematology & Oncology PhysicianPrimary
Internal Medicine — Hematology & Oncology
Code: 207RH0003X
319070-01(NY)N4530(TX)
Internal Medicine Physician
Internal Medicine
Code: 207R00000X
41493(TX)
CMS Specialties
PrimaryHEMATOLOGY/ONCOLOGY
Education
OTHER
Class of 1990
Research & Publications (20)
Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (obatoclax).
PMID 18451169·Cancer Res·2008
7-preclinical
Synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest in HER2-overexpressing breast cancer cells.
PMID 16505105·Mol Cancer Ther·2006
7-preclinical
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.
PMID 17097560·Cancer Cell·2006
7-preclinical
Development of a conditional in vivo model to evaluate the efficacy of small molecule inhibitors for the treatment of Raf-transformed hematopoietic cells.
PMID 16267021·Cancer Res·2005
7-preclinical
The novel triterpenoid CDDO-Me suppresses MAPK pathways and promotes p38 activation in acute myeloid leukemia cells.
PMID 15931262·Leukemia·2005
8-other
The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia.
PMID 15520199·Cancer Res·2004
8-other
Peroxisome proliferator-activated receptor gamma and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias.
PMID 15486192·Mol Cancer Ther·2004
8-other
Independent prognostic significance of day 21 cytogenetic findings in newly-diagnosed acute myeloid leukemia or refractory anemia with excess blasts.
PMID 12857550·Haematologica·2003
3-trial
Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins.
PMID 12200686·Leukemia·2002
7-preclinical
Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia.
PMID 11756188·Blood·2002
4-observational
Role of peroxisome proliferator-activated receptor-gamma in hematologic malignancies.
PMID 12042703·Curr Opin Hematol·2002
6-review
The anti-apoptotic genes Bcl-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells.
PMID 12139741·Br J Haematol·2002
8-other
Liposomal Bcl-2 antisense oligonucleotides enhance proliferation, sensitize acute myeloid leukemia to cytosine-arabinoside, and induce apoptosis independent of other antiapoptotic proteins.
PMID 10845930·Blood·2000
8-other
Antidiabetic therapies affect risk of pancreatic cancer.
PMID 19375425·Gastroenterology·2009
4-observational
Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML.
PMID 18955566·Blood·2009
7-preclinical
Concomitant inhibition of Mdm2-p53 interaction and Aurora kinases activates the p53-dependent postmitotic checkpoints and synergistically induces p53-mediated mitochondrial apoptosis along with reduced endoreduplication in acute myelogenous leukemia.
PMID 18633130·Blood·2008
8-other
Ceramide promotes apoptosis in chronic myelogenous leukemia-derived K562 cells by a mechanism involving caspase-8 and JNK.
PMID 18948750·Cell Cycle·2008
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1515 HOLCOMBE BLVD, 77030-4009
HOUSTON, TX 77030 - Phone
- (713) 792-6161
Quick Facts
- NPI
- 1518063486
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 3
- Locations
- 1
- Years in Practice
- 36
- Publications
- 20
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