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MICHAEL CONTINO, M.D.
M.D.
Emergency Medicine Physician
NPI: 1528021300Individual
Specialties, Licenses & Credentials
Emergency Medicine PhysicianPrimary
Emergency Medicine
Code: 207P00000X
G66386(CA)
Research & Publications (20)
F281, synthetic agonist of the sigma-2 receptor, induces Ca2+ efflux from the endoplasmic reticulum and mitochondria in SK-N-SH cells.
PMID 19187959·Cell Calcium·2009
7-preclinical
Multi-drug-resistance-reverting agents: 2-aryloxazole and 2-arylthiazole derivatives as potent BCRP or MRP1 inhibitors.
PMID 19140144·ChemMedChem·2009
7-preclinical
Design, synthesis, and binding affinities of potential positron emission tomography (PET) ligands with optimal lipophilicity for brain imaging of the dopamine D3 receptor. Part II.
PMID 19081257·Bioorg Med Chem·2009
8-other
Bicalutamide failure in prostate cancer treatment: involvement of Multi Drug Resistance proteins.
PMID 18992739·Eur J Pharmacol·2008
7-preclinical
Structural modifications of N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides: influence on lipophilicity and 5-HT7 receptor activity. Part III.
PMID 18800769·J Med Chem·2008
7-preclinical
Effect of some P-glycoprotein modulators on Rhodamine-123 absorption in guinea-pig ileum.
PMID 18524592·Bioorg Med Chem Lett·2008
7-preclinical
4-Biphenyl and 2-naphthyl substituted 6,7-dimethoxytetrahydroisoquinoline derivatives as potent P-gp modulators.
PMID 18276145·Bioorg Med Chem·2008
8-other
PB183, a sigma receptor ligand, as a potential PET probe for the imaging of prostate adenocarcinoma.
PMID 18276137·Bioorg Med Chem Lett·2008
7-preclinical
Tritium radiolabelling of PB28, a potent sigma-2 receptor ligand: pharmacokinetic and pharmacodynamic characterization.
PMID 18178434·Bioorg Med Chem Lett·2008
7-preclinical
Small P-gp modulating molecules: SAR studies on tetrahydroisoquinoline derivatives.
PMID 17936633·Bioorg Med Chem·2008
8-other
4-[omega-[4-arylpiperazin-1-yl]alkoxy]phenyl)imidazo[1,2-a]pyridine derivatives: fluorescent high-affinity dopamine D3 receptor ligands as potential probes for receptor visualization.
PMID 17850060·J Med Chem·2007
7-preclinical
Human epididymal and prostatic tracts of vas deferens: different contraction response to noradrenaline stimulation in isolated organ bath assay.
PMID 17900563·Eur J Pharmacol·2007
4-observational
Structure-activity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides, a class of 5-HT7 receptor agents. 2.
PMID 17649988·J Med Chem·2007
7-preclinical
The sigma-2 receptor agonist PB28 inhibits calcium release from the endoplasmic reticulum of SK-N-SH neuroblastoma cells.
PMID 16687172·Cell Calcium·2006
7-preclinical
Correlation between sigma2 receptor protein expression and histopathologic grade in human bladder cancer.
PMID 16005143·Cancer Lett·2006
4-observational
First structure-activity relationship study on dopamine D3 receptor agents with N-[4-(4-arylpiperazin-1-yl)butyl]arylcarboxamide structure.
PMID 16335915·J Med Chem·2005
7-preclinical
Distribution of sigma receptors in EMT-6 cells: preliminary biological evaluation of PB167 and potential for in-vivo PET.
PMID 16259778·J Pharm Pharmacol·2005
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- ONE HOAG DR, ECU DEPT
NEWPORT BEACH, CA 92663 - Phone
- (949) 764-5689
Quick Facts
- NPI
- 1528021300
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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